Genmab — Maj 2014

[Legolas23]

Året startede ud i 220...

[investor1989]

217 så vi er i +

[JKY_VH]

220,2 ?

[JKY_VH]

Rart at se Carnegie som næststørste nettokøber om end det kun er en brøkdel af Nordea´s nettokøb

[Solsen]

http://www.mpatient.org/dr-paul-richardson-2/

[Solsen]

So just focusing on daratumumab first, that antibody is now really moving forward in Phase III studies now actually as I speak, having completed very quick Phase I and II development, recognizing that the early Phase I of development to the antibody was necessarily very slow because this is a first-in-man experience

[Solsen]

So based upon that, we are now accelerating very quickly and we have combinations of dara with lenalidomide, combinations of dara coming forward now with bortezomib, and basically there will be combinations of dara with lenalidomide and bortezomib, the so-called RVD plus dara, and these will be very powerful platforms for future treatment.

[Solsen]

The initial results from lenalidomide plus dara in our own center, these studies are being led by my colleague, Jacob Laubach and Jacob is phenomenal in doing a wonderful job with all of these. Basically what he’s showing is that when you put daratumumab with lenalidomide, there’s tremendous activity being seen.

[Solsen]

Hence, similarly daratumumab even as a single-agent, just like our partners in the same trial who are actually from Denmark and Holland are showing exactly the same thing, as part of the same study, we’re all working as one team. But what we’re showing is that dara really works on its own, and dara combined with lenalidomide is very powerful as well.

[Solsen]

And then larger trials are currently ongoing led by our partners here in the US, Janssen who are leading these and moving these across the country so that this drug can get as quickly as possible to approval.

[Solsen]

Jf citatet ser det ud til at mono pivotal er fuldt rekrutteret.

[Solsen]

Så bliver ph3 kombi åbnet og der kommer milestones snart.

[Solsen]

Full steam ahead approval... !!!

[Solsen]

Men vi må forberede os på at SAR også kan tage markedsandel i større eller mindre omfang - men er 1-2 år bagud, som det ser ud nu.

[Solsen]

http://www.rigshospitalet.dk/NR/rdonlyres/30E272CA-B074-4266-9620-1B63FF96E1F7/0/Gen501Del2_Pinf.pdf i denne deltagerinformation omtales max 112 pts i ph1/2 forsøget

[bongobob]

ASCO. Første poster med Dara Len Dex klokken 20 i morgen (7 timer forskel fra 1PM)

[bongobob]

Det er den med de ufuldstændige 8/16 mg/kg de har rejst med i en evighed. Bliver godt at se nogle CR på den

[celsius]

Ja det blir et par sindssyge spændende dage vi har vente afsluttende med Jans præsentation på Jeffries tirsdag aften

[JKY_VH]

Enig og fortjent stemme, tak Solsen.

[Fantomas]

Jeg er også lige blevet færdig med den. Godt fundet frem, og en helt fortjent stemme op! Jeg tror det kan blive en rigtig god uge for os genmab aktionærer i næste uge, ser frem til ASCO og til at se hvad analytikerne, og alle de skarpe hoveder her på PI, har at sige til det!