Genmab — Maj 2014
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vi kan ikke få phase III data på ASCO.. Det første phase III studie er ikke engang startet med at indrulle patienter endnu
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I det mest optimistiske scenarie får vi pivotal data fra phase II BTD studiet ultimo 2014 og så en NDA filing engang i første halvdel af 2015
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Nordea går satme også til den
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Det er nok Novods kommentar om at Dara alene potentielt kan være over 400 kurspoint værd
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217 så vi er i +
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So just focusing on daratumumab first, that antibody is now really moving forward in Phase III studies now actually as I speak, having completed very quick Phase I and II development, recognizing that the early Phase I of development to the antibody was necessarily very slow because this is a first-in-man experience
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So based upon that, we are now accelerating very quickly and we have combinations of dara with lenalidomide, combinations of dara coming forward now with bortezomib, and basically there will be combinations of dara with lenalidomide and bortezomib, the so-called RVD plus dara, and these will be very powerful platforms for future treatment.
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The initial results from lenalidomide plus dara in our own center, these studies are being led by my colleague, Jacob Laubach and Jacob is phenomenal in doing a wonderful job with all of these. Basically what he’s showing is that when you put daratumumab with lenalidomide, there’s tremendous activity being seen.
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Hence, similarly daratumumab even as a single-agent, just like our partners in the same trial who are actually from Denmark and Holland are showing exactly the same thing, as part of the same study, we’re all working as one team. But what we’re showing is that dara really works on its own, and dara combined with lenalidomide is very powerful as well.
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