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Genmab — September 2013

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • D Offline
    D Offline
    deleted-user
    wrote on sidst redigeret af
    #104

    i gamle dage (før 08) sagde vi at fase 3 var 75% sandsynlighed. Jeg kan huske at jeg har set noget primary endpoint statiistik. Og det er ikke 75% der nå det. Men når man er kommet så langt i kræft så er det mere end 50% vil jeg tro.

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    • G Offline
      G Offline
      gentogen
      wrote on sidst redigeret af
      #105

      404 Not Found

      favicon

      (files.shareholder.com)

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      • G Offline
        G Offline
        gentogen
        wrote on sidst redigeret af
        #106

        ofatumumab in combination with bendamustine
        is an effective and tolerable therapy, providing high response rates
        and an acceptable safety profile for patients with either previously
        untreated CLL who are inappropriate for fludarabine-based therapy,
        or patients with relapsed CLL

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        • G Offline
          G Offline
          gentogen
          wrote on sidst redigeret af
          #107

          Investigator-assessed ORR was 95% (CR rate 43%) in the previously
          untreated population and 74% (CR rate 11%) in the relapsed
          population. 56% of patients in the in the previously untreated
          population who had an investigator-assessed CR

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          • G Offline
            G Offline
            gentogen
            wrote on sidst redigeret af
            #108

            No deaths were reported in the previously untreated population a

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            • D Offline
              D Offline
              deleted-user
              wrote on sidst redigeret af
              #109

              hvor kommer den poster fra?

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              • D Offline
                D Offline
                deleted-user
                wrote on sidst redigeret af
                #110

                jeg synes cr er rigtigt stærke

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                • G Offline
                  G Offline
                  gentogen
                  wrote on sidst redigeret af
                  #111

                  Genmabs hjemmeside. Der er lidt forskellige udregninger af CR, men generelt ser det godt ud, ja. Jeg har endnu ikke nærlæst.

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                  • G Offline
                    G Offline
                    gentogen
                    wrote on sidst redigeret af
                    #112

                    se under events eller under investor downloads

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                    • G Offline
                      G Offline
                      gentogen
                      wrote on sidst redigeret af
                      #113

                      http://ir.genmab.com/downloads.cfm

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                      • D Offline
                        D Offline
                        deleted-user
                        wrote on sidst redigeret af
                        #114

                        tak

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                        • bongobobB Offline
                          bongobobB Offline
                          bongobob
                          wrote on sidst redigeret af
                          #115

                          Dobbelt op på CR ifht Rituximab http://www.ncbi.nlm.nih.gov/pubmed/22869884

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                          • J Offline
                            J Offline
                            JKY_VH
                            wrote on sidst redigeret af
                            #116

                            aka, tak for feedback omkring sandsynligheder i fase 3. Det understreger min pointe nemlig, at det ikke er rimeligt at sætte sandsynligheden = 0 🙂

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                            • JørgenVarnæsJ Offline
                              JørgenVarnæsJ Offline
                              JørgenVarnæs
                              wrote on sidst redigeret af
                              #117

                              er det ikke de data Jan sagde at GEN ville præsentere på iwcll i Køln? Det ser dælme godt ud!

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                              • bongobobB Offline
                                bongobobB Offline
                                bongobob
                                wrote on sidst redigeret af
                                #118

                                Hvis man ser på Previously untreatet delen må man kunne forvente noget tilsvarende for det ph3 studie vi fik top line for i maj

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                                • MadsSkjernM Offline
                                  MadsSkjernM Offline
                                  MadsSkjern
                                  wrote on sidst redigeret af
                                  #119

                                  JV, det er data fra ofa-bendamustine fase 2. De data han har lovet, men flyttet til ASH er ofa-clorambucil

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                                  • MadsSkjernM Offline
                                    MadsSkjernM Offline
                                    MadsSkjern
                                    wrote on sidst redigeret af
                                    #120

                                    Men samme indikation.

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #121

                                      Bendamustine er mere effektiv kemo end chlorambucil, men har også flere alvorlige bivirkningen

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                                      • JørgenVarnæsJ Offline
                                        JørgenVarnæsJ Offline
                                        JørgenVarnæs
                                        wrote on sidst redigeret af
                                        #122

                                        Hej MAds - der var oprindeligt to datasæt på iwcll - og ofa+chlorambucil fase III blev flyttet mens bendamustine blev på iwcll - som jeg husker det

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                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #123

                                          Nemlig

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