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  4. Genmab — Juli 2025

Genmab — Juli 2025

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • L Offline
    L Offline
    lahn1
    wrote on sidst redigeret af
    #132

    Thx EL, for bringing that abstract up, not one i noticed a lot previous.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #133

      yes, i was confused when the last update of the GEN1059 deleted the arm with Pembro so shortly after that abstract https://clinicaltrials.gov/study/NCT06150183?tab=history&a=13&b=14&compareMode=sideBySide#version-content-panel , worried it was the end of 1059. Now it seems they just switched Pembro with BNT327 and immediately hope springs again lol

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      • L Offline
        L Offline
        lahn1
        wrote on sidst redigeret af
        #134

        We don’t wont them to get a habit of terminating pipeline candidates

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        • J Offline
          J Offline
          JKY_VH
          wrote on sidst redigeret af
          #135

          Fra MW "Genmab har fået hævet kursmålet til 1916 kr. fra 1785 kr. hos storbanken Goldman Sachs, som dog holder fast i sin neutrale anbefaling af aktien.

          Det fremgår af Bloomberg News.

          Trods den neutrale anbefaling indikerer kursmålet 32,2 pct. potentielt afkast over de kommende 12 måneder, efter at Genmab-aktien onsdag steg 4,7 pct. til 1449,50 kr."

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #136

            the Tepezza EMA EPAR - Public assessment report for those interested -153 pages- https://www.ema.europa.eu/en/documents/assessment-report/tepezza-epar-public-assessment-report_en.pdf

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #137

              Roche YTD June 2025 https://assets.roche.com/f/176343/x/3e163d97e6/250724_ir_hy.pdf CHF mn Ocrevus 3,506 8% , Columvi 123 88% , Lunsumio 48 33%

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              • L Offline
                L Offline
                lahn1
                wrote on sidst redigeret af
                #138

                No doubt, AI like chat gpt is making mankind dummer, but I do love getting a one page summery of a 153 page report. LOL 🙂

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                • P Offline
                  P Offline
                  ProinvestorNEWS
                  wrote on sidst redigeret af
                  #139

                  I dag, torsdag den 24. juli 2025, er en helt speciel dag for mange aktieinvestorer. For C25 er efter en hård 2025 endelig i plus igen. Helge Larsen ser på årsagerne og omtaler Novo Nordisk, Zealand Pharma, ISS, Vestas, Carlsberg og Bavarian Nordic. Og så slutter han af med flere gode nyheder, her fra Anavex, som i går steg 20 procent. Kort video: https://proinvestor.com/boards/127342/

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #140

                    Small new trial - A Study of Epcoritamab and Ibrutinib in People With Central Nervous System Lymphoma (CNSL) https://clinicaltrials.gov/study/NCT07082868

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                    • W Offline
                      W Offline
                      w
                      wrote on sidst redigeret af
                      #141

                      Uden jinxe for meget, så har vi vel brudt den lange nedtrend for første gang i 2.5år

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                      • P Offline
                        P Offline
                        ProinvestorNEWS
                        wrote on sidst redigeret af
                        #142

                        Sanofi's Sarclisa Combination Gets EU Approval For Treating Newly Diagnosed Multiple Myeloma https://proinvestor.com/investornyt/1342936/sanofis-sarclisa-combination-gets-eu-approval-for-treating-newly-diagnosed-multiple-myeloma

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                        • B Offline
                          B Offline
                          BSinvest
                          wrote on sidst redigeret af
                          #143

                          w... Aktien stadig er i en nedadgående trend. Afvent et brud over 1.650 DKK for at bekræfte en potentiel vending.

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                          • B Offline
                            B Offline
                            BSinvest
                            wrote on sidst redigeret af
                            #144

                            Vendingen skal helst ske med stigende RSI og øget handelsvolumen for at bekræfte at trenden for alvor er stigende.

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #145

                              A hexamerization-enhanced, Fc-silenced agonistic CD27 antibody amplifies T-cell effector functions as single agent and in combination with PD-1 blockade https://www.nature.com/articles/s41598-025-11990-z

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                              • G Offline
                                G Offline
                                gentogen
                                wrote on sidst redigeret af
                                #146

                                The study of this was terminated prior to the start of the Dose Expansion Phase.NCT05435339. Many positive things in the article, but I kind of lack a coclusion about the development as ended or not?

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #147

                                  They discontinued the clinical development.

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #148

                                    this is what it said last august24: Following a strategic evaluation of GEN1053 within the context of
                                    Genmab’s and BioNTech’s portfolios, a decision was made to discontinue the Phase 1/2 clinical trial
                                    (NCT05435339) of GEN1053 in solid tumors. Preclinical activities remain ongoing.

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #149

                                      whether those preclinical activities aim to return with something on Hexabody-CD27 I don't know (but i doubt it). Maybe it is to get more info on the Hexabody technology

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #150

                                        But both Özlem Türeci & Uğur Şahin from biontech co-authored it, so they must have deemed it of interest

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                                        • G Offline
                                          G Offline
                                          gentogen
                                          wrote on sidst redigeret af
                                          #151

                                          Thanks a lot for the extra info.

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