Bavarian Nordic — Juni 2024
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Mpox og vaccination: fra Jenner til MVA-BN https://vih-org.translate.goog/maladies-emergentes/20240627/mpox-et-vaccination-de-jenner-au-mva-bn/?_x_tr_sl=fr&_x_tr_tl=da&_x_tr_hl=da&_x_tr_pto=sc - lidt historie
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'Fortsat bestræbelser på at svække de originale stammer førte til produktionen af to stammer, der blev brugt som 3. generations vacciner : LC16m8 udviklet af Kaketsuken
i Japan og MVA (Modified Ankara Vaccine) stammen udviklet af Bavarian Nordic i Danmark' -
Tak WT. Så nu er spørgsmålet, hvilke af disse to vacciner er mest effektiv i forhold til den nye variant?
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Ja det må tiden vise, vi satser på Bavas
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Der skulle i øvrigt være tale om clade Ib variant, som nu florerer rundt dernede
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den fra 2022 var clade II
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jep
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Kort video:
Zealand Pharma, Novo, Gubra, Bavarian, ALK , Hansa Biopharma https://proinvestor.com/boards/121107 -
OVERBLIK: Disse selskaber er shortet på det danske aktiemarked https://proinvestor.com/investornyt/1178786/overblik-disse-selskaber-er-shortet-pa-det-danske-aktiemarked
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Millennium International Management LP har en kort nettoposition på 0,72% i aktiekapitalen udstedt af Bavarian Nordic A/S, en øgning på 0,1%, det lyder ikke af meget, men er trods alt en del. https://oam.finanstilsynet.dk/#!/announcement-details?Id=DFSAAnnouncement%2Fb75939c4-9e6a-4ec7-b72f-b19c009abbac
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'We've got monkeypox in the community': Locally-acquired mpox infections up in Australia'
'We've got monkeypox in the community': Locally-acquired mpox infections up in Australia
Health experts are calling for Australians to get vaccinated as an outbreak of mpox, formerly known as monkeypox, sweeps the country. Meanwhile, a deadly new subvariant is sweeping the Democratic Republic of Congo.
SBS News (www.sbs.com.au)
(SBS News)
Health experts are calling for Australians to get vaccinated as an outbreak of mpox ....
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"The current outbreak started around Anzac Day in Melbourne, so it's been running for a couple of months now. Victoria's up at 50 cases currently, and then there's also been a significant number in Brisbane and then a few cases in Adelaide and in Sydney also."
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Er fortsat lidt overrasket over, at LC16-vaccinen godkendes af DRC, når den fx ikke er et valg hos CDC https://www.cdc.gov/poxvirus/mpox/vaccines/vaccine-recommendations.html Vi har diskuteret LC16 før her i chatten - og nu som før, så er LC16 ikke egnet for bl.a. immunkomprimerede og den kræver, at alle patienter og deres historik eksamineres grundigt inden evt. anvendelse grundet bivirkningernes severity. https://www.hosp.ncgm.go.jp/isc/vaccines/MNK/Vaccination_Procedure_Guideline_for_Lc16.pdf
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Ligner en tur ned omkring 155 igen. Skyldes det alene LC16
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Det er selvfølge "nemmere" blot at skulle vaccinere 1 gang med freeze dried, men metoden (bifurcaated needle) er = ACAM + omstændeligt ift sprøjte. Sammenligning af de 3 typer mpox- vacciner fra 2022 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9500691/ Kan forstå behovet for et alternativ, hvis akut behov opstår, men en begrundet vaccine-skepsis i mange afrikanske lande vil muligvis øges, hvis vaccine, der ikke anbefales / anvendes i vestlige lande, nu erklæres "god nok" til afrika...
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