Genmab — Juni 2025
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Hemab Therapeutics to Present Clinical and Preclinical Data from Multiple Bleeding Disorder Programs at the ISTH 2025 Congress - HealthCap
Sutacimig (formerly HMB-001) continues to demonstrate promising interim safety, PK, and efficacy Phase 2 results in Glanzmann thrombasthenia and is granted its International Non-Proprietary Name designation by WHO HMB-002 shows promise in Von Willebrand disease with initial proof of mechanism clinical data from patients in ongoing VELORA Pioneer study, supported by comprehensive non-clinical package including […]
HealthCap (www.healthcap.eu)
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Interim results show HMB-001 significantly reduces frequency of bleeding events with a favorable safety profile, supporting its potential as a novel prophylactic treatment for GT. HMB-001’s subcutaneous dosing offers a proactive alternative to reactive GT care, addressing a critical unmet need.
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The EPCORE NHL-2 trial: epcoritamab plus GemOx in transplant-ineligible R/R DLBCL https://www.youtube.com/watch?v=w1GmTshxnbU
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ICML 2025 | Results from EPCORE NHL-2 trial of epcoritamab + R-CHOP for previously untreated DLBCL https://www.youtube.com/watch?v=9sco80a47i4
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DARZALEX
(daratumumab) receives the first positive CHMP opinion for patients with high-risk smouldering multiple myeloma https://www.globenewswire.com/news-release/2025/06/20/3102621/0/en/DARZALEX-daratumumab-receives-the-first-positive-CHMP-opinion-for-patients-with-high-risk-smouldering-multiple-myeloma.html -
Lymphoma Hub
@lymphomahub 18ICML Fixed-duration epcoritamab monotherapy led to high response rates (ORR, 78%; CR rate, 70%) and a manageable safety profile in older, anthracycline-ineligible patients with LBCL. These results suggest that epcoritamab monotherapy is a promising chemotherapy-free treatment option for this patient population. https://x.com/lymphomahub/status/1935994273180025220 -
Godmorgen
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Novo Nordisk med lovende nyt om mim8 https://www.novonordisk.com/content/nncorp/global/en/news-and-media/news-and-ir-materials/news-details.html?id=916355
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Roche closes in on Epkinly with SC Lunsumio data in lymphoma https://firstwordpharma.com/story/5975116
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small new trial - A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma (ECLAT) https://clinicaltrials.gov/study/NCT07030699
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Så er der spændende nyt i sagen mod Abbvies. Se indlæg i debatten. Defendants respectively request that AbbVie's Complaint be dismissed. https://proinvestor.com/boards/126977/
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Genmab-kræftmiddel på vej mod blockbusterstatus https://proinvestor.com/investornyt/1332433/genmab-kraeftmiddel-pa-vej-mod-blockbusterstatus (artiklen kræver ikke abonnement)
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FRONTIER5 direct switch study: Safety of initiating Mim8 prophylaxis without washout of Emicizumab https://sciencehub.novonordisk.com/congresses/isth2025/johannes-oldenburg.html
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ISTH 2025
21 - 25 June 2025
Mim8 enhances procoagulant activity of select hemophilia B-causing factor IX variants https://sciencehub.novonordisk.com/congresses/isth2025/sebastian-leyes-porello.html
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