Genmab — Juni 2025
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EHA 2025 – J&J claims an extramedullary edge
The company sees an improvement with a Tecvayli/Talvey combo vs either monotherapy. https://www.oncologypipeline.com/apexonco/eha-2025-jj-claims-extramedullary-edge -
Epcoritamab Plus Chemoimmunotherapy Yields 87% Response Rate in R/R DLBCL; 65% Proceed to Transplant https://www.ajmc.com/view/epcoritamab-plus-chemoimmunotherapy-yields-87-response-rate-in-r-r-dlbcl-65-proceed-to-transplant
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EHA 2025 | How effective is epcoritamab + R-ICE in patients with R/R DLBCL who are ASCT eligible? https://www.youtube.com/watch?v=bCdPlWOjJ1M
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RITUXIMAB AND EPCORITAMAB AS FIRST-LINE THERAPY FOR PATIENTS WITH HIGH-TUMOR BURDEN FOLLICULAR LYMPHOMA: FIRST RESULTS OF A MULTICENTER PHASE II TRIAL https://onlinelibrary.wiley.com/doi/10.1002/hon.70094_227 -from the
18th International Conference on Malignant Lymphoma https://onlinelibrary.wiley.com/toc/10991069/2025/43/S3
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Hemab Therapeutics
@Hemab_TxICYMI: Last week we announced the International Non-Proprietary Name (INN) sutacimig for HMB-001 — marking the first-ever INN for a treatment designated for Glanzmann thrombasthenia.https://x.com/Hemab_Tx/status/1935293889662898321
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Hemab Therapeutics to Present Clinical and Preclinical Data from Multiple Bleeding Disorder Programs at the ISTH 2025 Congress - HealthCap
Sutacimig (formerly HMB-001) continues to demonstrate promising interim safety, PK, and efficacy Phase 2 results in Glanzmann thrombasthenia and is granted its International Non-Proprietary Name designation by WHO HMB-002 shows promise in Von Willebrand disease with initial proof of mechanism clinical data from patients in ongoing VELORA Pioneer study, supported by comprehensive non-clinical package including […]
HealthCap (www.healthcap.eu)
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Interim results show HMB-001 significantly reduces frequency of bleeding events with a favorable safety profile, supporting its potential as a novel prophylactic treatment for GT. HMB-001’s subcutaneous dosing offers a proactive alternative to reactive GT care, addressing a critical unmet need.
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The EPCORE NHL-2 trial: epcoritamab plus GemOx in transplant-ineligible R/R DLBCL https://www.youtube.com/watch?v=w1GmTshxnbU
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ICML 2025 | Results from EPCORE NHL-2 trial of epcoritamab + R-CHOP for previously untreated DLBCL https://www.youtube.com/watch?v=9sco80a47i4
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DARZALEX
(daratumumab) receives the first positive CHMP opinion for patients with high-risk smouldering multiple myeloma https://www.globenewswire.com/news-release/2025/06/20/3102621/0/en/DARZALEX-daratumumab-receives-the-first-positive-CHMP-opinion-for-patients-with-high-risk-smouldering-multiple-myeloma.html -
Lymphoma Hub
@lymphomahub 18ICML Fixed-duration epcoritamab monotherapy led to high response rates (ORR, 78%; CR rate, 70%) and a manageable safety profile in older, anthracycline-ineligible patients with LBCL. These results suggest that epcoritamab monotherapy is a promising chemotherapy-free treatment option for this patient population. https://x.com/lymphomahub/status/1935994273180025220 -
Godmorgen
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Novo Nordisk med lovende nyt om mim8 https://www.novonordisk.com/content/nncorp/global/en/news-and-media/news-and-ir-materials/news-details.html?id=916355
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Roche closes in on Epkinly with SC Lunsumio data in lymphoma https://firstwordpharma.com/story/5975116
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small new trial - A Study of Epcoritamab With Lenalidomide and Tafasitamab in People With Diffuse Large B Cell Lymphoma (ECLAT) https://clinicaltrials.gov/study/NCT07030699
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