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  4. Genmab — Februar 2025

Genmab — Februar 2025

Planlagt Fastgjort Låst Flyttet Genmab
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  • L Offline
    L Offline
    lahn1
    wrote on sidst redigeret af
    #493

    EL, that is super interesting. But Jan did not sound like he thinks there will be a market for Erzo at the earnings cal when asked what if ... would Gmab develop Erzo further. Oddly if he thinks the Erzo is such a good drug. But I think I would prefer Gmab hold on to Erzo rather than make a new Erzo agreement with JnJ for alle indications with a low single digit royalty.

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    • S Offline
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      Sukkeralf
      wrote on sidst redigeret af
      #494

      E L - today these patients have alternatives like tec and tal. Then maybe it should be in powerful combinations. Or if all know HexaCD38 works better than Darzalex it could be off label sales in other lines that approved for.

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      • S Offline
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        Sukkeralf
        wrote on sidst redigeret af
        #495

        But we also need sc dosing probably - do Janssen have sc dosing possibilities left at Halozymes?

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        • L Offline
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          lahn1
          wrote on sidst redigeret af
          #496

          “I think the data looks brilliant. I mean, where you would have told me 10 years ago that it is possible to make a more positive antibody than daratumumab, I would have laughed at it because I wouldn't have believed it because daratumumab is a unique antibody, is one of the best therapeutic antibodies developed over the last decades.

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          • L Offline
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            lahn1
            wrote on sidst redigeret af
            #497

            So I think in the industry, 3 years from now, it's going to be 1 of the top 3 biggest cancer drugs on earth. Right now it's the biggest product for JNJ and then to have a better one, which is differentiated. I think it's potentially super exciting.”

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            • J Offline
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              JKY_VH
              wrote on sidst redigeret af
              #498

              lahn1, det understreger vel at hvis ikke JNJ/Genmab udvikler et bedre præparat end Dara, så gør andre det kannibalisering eller ej.

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              • exitnuE Offline
                exitnuE Offline
                exitnu
                wrote on sidst redigeret af
                #499

                Genmab (GMAB) Gets a Hold from Morgan Stanley, price target of $31.00 (Feb. 18, 2025, 07:16 AM).

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                • E Offline
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                  E_L
                  wrote on sidst redigeret af
                  #500

                  whatever happens, one would expect HexaCD38 to be marketed in combination anyway, no? and if that combo is with Tec or Tal; all the better

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                  • L Offline
                    L Offline
                    lahn1
                    wrote on sidst redigeret af
                    #501

                    yes Jan eluted to that point. Treatment is al about combination.

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                    • L Offline
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                      lahn1
                      wrote on sidst redigeret af
                      #502

                      Ja enten disrupter du dig selv eller også disrupter andre dig, period !

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                      • S Offline
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                        Sukkeralf
                        wrote on sidst redigeret af
                        #503

                        Yes but if Genmab is doing th clinical trials they probably need to buy tec and tal - so its so much easier if Janssen takes the option

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                        • E Offline
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                          E_L
                          wrote on sidst redigeret af
                          #504

                          it is definitely easier; i think we established that long time ago. And best for the short term share price reaction. And my blood pressure... (whether JNJ would or would not sponsor the Tec or Tal , is really a
                          minor issue i would think)

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                          • E Offline
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                            E_L
                            wrote on sidst redigeret af
                            #505

                            New trial - eal-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma / EpcoReal: A Multi-country, Prospective Observational Study of Epcoritamab in NHL Comprising Two Patient Cohorts (3L+ (D)LBCL and 3L+ FL) https://clinicaltrials.gov/study/NCT06830759

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                            • G Offline
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                              gentogen
                              wrote on sidst redigeret af
                              #506

                              Daratumumab is increasingly used in first-line, and soon patients that relapse while on daratumumab will become a common challenge.

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                              • G Offline
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                                gentogen
                                wrote on sidst redigeret af
                                #507

                                Link Preview Image
                                ScienceDirect

                                favicon

                                (www.sciencedirect.com)

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                                • P Offline
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                                  ProinvestorNEWS
                                  wrote on sidst redigeret af
                                  #508

                                  Teknisk: Genmab i brud op gennem vigtige modstande, fortsætter op i USA https://proinvestor.com/investornyt/1279889/teknisk-genmab-i-brud-op-gennem-vigtige-modstande-fortsaetter-op-i-usa

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                                  • E Offline
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                                    E_L
                                    wrote on sidst redigeret af
                                    #509

                                    Leo Habets
                                    @L_Habets
                                    Daratumumab Seit einiger Zeit behandeln wir Post, COVID, Post Vac und MEC FS Patienten mit Daratumumab wir haben jetzt insgesamt sieben Patienten in der Behandlung https://x.com/L_Habets/status/1891069465686634514 https://x.com/L_Habets/status/1891210734530400443

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                                    • B Offline
                                      B Offline
                                      bikube
                                      wrote on sidst redigeret af
                                      #510

                                      die Behandlung ist teuer, die kostet 20000€ fyr 4 gaben. Det er vist første gang, jeg har set en kontant pris på Dara.

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #511

                                        TipRanks
                                        Feb. 19, 2025, 01:35 AM
                                        In a report released today, Emily Field from Barclays maintained a Buy rating on Genmab A/S
                                        , with a price target of DKK2,100.00.

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #512

                                          looks like we will get an Acasunlimab Poster at the European Lung Cancer Congress at the end of the March https://cslide.ctimeetingtech.com/coasis_21204/attendee/confcal/presentation/list?q=acasunlimab Also a few for amivantamab, also orals

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