Genmab — Januar 2025
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Cancer vaccines compensate for the insufficient induction of protective tumor-specific immunity of CD3 bispecific antibody therapy https://jitc.bmj.com/content/13/1/e010331
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We demonstrate that a combination of CD3 bsAbs with tumor-specific vaccination improves survival against primary tumors and, importantly, also induces durable antitumor responses that confer protection from rechallenge in immunologically “hot” as well as “cold” solid tumor models.
This study provides a strong rationale for the combination of CD3 bsAbs and tumor-specific vaccination. In light of recent clinical successes of the therapeutic messenger RNA-based cancer vaccines, we advocate furthe
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New trial : A First-in-Human Trial of Safety and Efficacy of GEN1078 in Participants With Solid Tumors https://clinicaltrials.gov/study/NCT06771921
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Target not disclosed yet. 'estimated trial duration is 8 months for an individual participant /
The treatment duration will be an estimated 3-month treatment period > makes me think this is for a very serious disease? and maybe expect relative toxic drug? -
AbCellera Expands Collaboration with AbbVie to Develop Novel T-Cell Engagers for Oncology https://www.businesswire.com/news/home/20250113347375/en/AbCellera-Expands-Collaboration-with-AbbVie-to-Develop-Novel-T-Cell-Engagers-for-Oncology?utm_campaign=shareaholic&utm_medium=twitter&utm_source=socialnetwork
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Simcere Zaiming and AbbVie Announce Partnership to Develop a Novel Trispecific Antibody Candidate in Multiple Myeloma https://www.prnewswire.com/news-releases/simcere-zaiming-and-abbvie-announce-partnership-to-develop-a-novel-trispecific-antibody-candidate-in-multiple-myeloma-302349311.html
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JNJ have the transcript also on their website https://s203.q4cdn.com/636242992/files/doc_downloads/2024/09/jnj-usq_transcript_2024-09-04.pdf
, JPM not there yet. need stronger coffee...Hello! It looks like you're interested in this conversation, but you don't have an account yet.
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