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  4. Genmab — Januar 2025

Genmab — Januar 2025

Planlagt Fastgjort Låst Flyttet Genmab
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  • J Offline
    J Offline
    JKY_VH
    wrote on sidst redigeret af
    #96

    aktiestrateg i Jyske Bank. “Markedet fokuserer udelukkende på nyt om Hexabody-CD38, og det mener vi er fejlagtigt. Vi ser stadig et pænt potentiale i Genmab. Aktien er faldet så meget, at du får hele deres pipeline og faktisk også nogle lancerede produkter til nul kroner,” siger hun og tilføjer:

    “Forhåbentligt kan udviklingen vende i aktien, hvis der kommer en partnerskabsaftale. Så vil aktien nok stige med 20-25 pct.” https://borsen.dk/nyheder/investor/c25-pa-tilbud-her-er-de-billigste-aktier?

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    • J Offline
      J Offline
      JKY_VH
      wrote on sidst redigeret af
      #97

      Det må godt inspirere "datteren" Johnson & Johnson rygtes tæt på milliardopkøb https://borsen.dk/nyheder/virksomheder/johnson-johnson-rygtes-taet-pa-milliardopkob?b_source=borsen&b_medium=row_0&b_campaign=list_1

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #98

        Cancer vaccines compensate for the insufficient induction of protective tumor-specific immunity of CD3 bispecific antibody therapy https://jitc.bmj.com/content/13/1/e010331

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #99

          We demonstrate that a combination of CD3 bsAbs with tumor-specific vaccination improves survival against primary tumors and, importantly, also induces durable antitumor responses that confer protection from rechallenge in immunologically “hot” as well as “cold” solid tumor models.

          This study provides a strong rationale for the combination of CD3 bsAbs and tumor-specific vaccination. In light of recent clinical successes of the therapeutic messenger RNA-based cancer vaccines, we advocate furthe

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #100

            further translational implementation of our combinatorial concept.

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #101

              New trial : A First-in-Human Trial of Safety and Efficacy of GEN1078 in Participants With Solid Tumors https://clinicaltrials.gov/study/NCT06771921

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #102

                Target not disclosed yet. 'estimated trial duration is 8 months for an individual participant /
                The treatment duration will be an estimated 3-month treatment period > makes me think this is for a very serious disease? and maybe expect relative toxic drug?

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #103

                  Exclusion Criteria : Prior treatment with aTIGIT, aPD1, aPDL1, aLAG3,
                  aCTLA-4 ; may give some indication to the target?

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #104

                    Moderna opening -20% on a revenue update, @ $34, i think they traded near $500 at the top...

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #105

                      AbCellera Expands Collaboration with AbbVie to Develop Novel T-Cell Engagers for Oncology https://www.businesswire.com/news/home/20250113347375/en/AbCellera-Expands-Collaboration-with-AbbVie-to-Develop-Novel-T-Cell-Engagers-for-Oncology?utm_campaign=shareaholic&utm_medium=twitter&utm_source=socialnetwork

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #106

                        Simcere Zaiming and AbbVie Announce Partnership to Develop a Novel Trispecific Antibody Candidate in Multiple Myeloma https://www.prnewswire.com/news-releases/simcere-zaiming-and-abbvie-announce-partnership-to-develop-a-novel-trispecific-antibody-candidate-in-multiple-myeloma-302349311.html

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                        • E Offline
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                          E_L
                          wrote on sidst redigeret af
                          #107

                          that Genmab and AbbVie collaboration doesn't seem to be going anywhere besides Epco...

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #108

                            4,5 years without any information about this part of the deal - so guess they have not done anything at all. Which of them to blame?

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #109

                              my guess is that a 50:50 collaboration is too expensive for a company like Abbvie, unless they get offered an antibody that really knocks it out of the park...

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                              • E Offline
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                                E_L
                                wrote on sidst redigeret af
                                #110

                                i had hopes for a duohexabody or hexelect, but alas... not expecting much anymore , besides possibly another disease area with Epco

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                                • E Offline
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                                  E_L
                                  wrote on sidst redigeret af
                                  #111

                                  the other side is offcourse also; IF Genmab has a great idea; do they still want to share it... or try to develop it themselves...

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #112

                                    https://www.linkedin.com/posts/janvandewinkel_innovation-antibodyscience-jpm2025-activity-7284646692912562179-Dgdb?utm_source=share&utm_medium=member_ios Winkel

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                                    • B Offline
                                      B Offline
                                      bikube
                                      wrote on sidst redigeret af
                                      #113

                                      JnJ har udsendt Transcript fra J P Morgans Healthcare Conference, den ligger på Seeking Alfa. Er der ikke noget fra Genmab endnu ?

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #114

                                        JNJ have the transcript also on their website https://s203.q4cdn.com/636242992/files/doc_downloads/2024/09/jnj-usq_transcript_2024-09-04.pdf

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #115

                                          Genmab will present tonight

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