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  4. Genmab — December 2024

Genmab — December 2024

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • W Offline
    W Offline
    w
    wrote on sidst redigeret af
    #270

    Access to this page has been denied

    px-captcha

    favicon

    (seekingalpha.com)

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    • StockBullS Offline
      StockBullS Offline
      StockBull
      wrote on sidst redigeret af
      #271

      der er en stigende debat om, hvordan sundhedssektoren og store medicinalfirmaer, der ikke integrerer AI i deres processer, kan miste konkurrenceevne. AI har potentiale til at revolutionere forskning, diagnose og behandling, hvilket kan give dem, der omfavner teknologien, en betydelig fordel. Investorer er ofte på udkig efter virksomheder, der innoverer og tilpasser sig nye teknologier, hvilket kan påvirke aktiekurserne i fremtiden. Håber Genmab køre fuld skrue m.h.t at implementere AI

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      • R Offline
        R Offline
        Raun
        wrote on sidst redigeret af
        #272

        Det er meldt ud for et stykke tid siden at Genmab satser stort på AI

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        • R Offline
          R Offline
          Raun
          wrote on sidst redigeret af
          #273

          Link Preview Image
          Genmab vil udvide AI-afdeling

          Hisham Hamadeh, der er global chef for datavidenskab og AI i Genmab, forventer at 2025 bliver et vendepunkt.

          favicon

          (medwatch.dk)

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #274

            ASH24 718 Safety and Efficacy of Mim8 Prophylaxis Administered Once Every Two Weeks for Patients with Hemophilia A with or without Inhibitors: Interim Analysis of the FRONTIER4 Open-Label Extension Study https://ash.confex.com/ash/2024/webprogram/Paper198617.html

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #275

              Tadashi Matsushita, MD, PhD: Reducing Treatment Burden in Hemophilia A - findings from the OLE FRONTIER4 study of Mim8. https://www.hcplive.com/view/matsushita-reducing-treatment-burden-hemophilia-a

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #276

                ASH24 1212 Mim8 Prophylaxis Beyond Bleeding: Investigating Multifaceted, Patient-Reported Outcomes for Hemophilia A in the FRONTIER2 Study https://ash.confex.com/ash/2024/webprogram/Paper198395.html

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #277

                  Mim8 Improved Patient Outcomes in Hemophilia A in FRONTIER2 Trial https://www.rarediseaseadvisor.com/news/mim8-improved-patient-outcomes-in-hemophilia-a-in-frontier2-trial/

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #278

                    Tri-specific Antibody SAR442257 in RRMM - further development halted

                    • https://www.youtube.com/watch?v=7NzP-E9WnRo
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                    • G Offline
                      G Offline
                      gentogen
                      wrote on sidst redigeret af
                      #279

                      This Phase 1 study of SAR'257 showed an anti-tumor response in a small number of pts from the rrMM and rrNHL cohorts. Due to safety concerns, in particular high rates of EBV and CMV reactivation and recurrent episodes of CRS in the higher dose levels, the study was terminated during dose escalation

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                      • G Offline
                        G Offline
                        gentogen
                        wrote on sidst redigeret af
                        #280

                        the overall response rate (ORR), defined as partial response (PR) or better, was 5%......

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #281

                          ASH24 T Cells from CLL Patients on Venetoclax Mount Potent Cytotoxic Responses in
                          Combination with Epcoritamab, a CD20/CD3 Bispecific Antibody https://www.postersessiononline.eu/173580348_eu/congresos/ASH2024/aula/-SUN_3231_ASH2024.pdf https://ashpublications.org/blood/article/144/Supplement 1/3231/533852/T-Cells-from-CLL-Patients-on-Venetoclax-Mount

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #282

                            further ASH24 presentations /posters via https://www.genmabmedicalaffairs.com/congress?filv1=21

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                            • nohopeN Offline
                              nohopeN Offline
                              nohope
                              wrote on sidst redigeret af
                              #283

                              Hypotese: JnJ meddeler, at Erzo er interessant, men kun til halvdelen af den royalty, som der var aftalt ?

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #284

                                i have had something like this in the back of my mind as well. it may not be a binary yes or no decision, there may be a gray zone where either JNJ or Genmab tries to adjust the agreement... but that really is a futile discussion for now, until we'll hear what happens

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #285

                                  at the end of the day, there is a legal document; if JNJ only wants to pay half Genmab can say no if they think they can make more money with it themselves. they'll have to make a choice.

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                                  • nohopeN Offline
                                    nohopeN Offline
                                    nohope
                                    wrote on sidst redigeret af
                                    #286

                                    Selv halv betaling ville være mere end GENMAB kunne opnå ved selv at promovere Erzo i andre indikationer.

                                    1 Reply Last reply
                                    0
                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #287

                                      We don't know that. I argued here before that it may very well be that it is actually more valuable in the hands of genmab. But at a greater risk. But only genmab has a reasonable insight into this. My preference for now is for jnj to opt in as that
                                      may be most beneficial for short term stock prices

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #288

                                        In that case its a NO from Genmab. The decision is binary. Is Erzo interesting or no and the terms we have discussed.

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                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #289

                                          No more gifts to JNJ.

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                                          0

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