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  4. Genmab — Oktober 2024

Genmab — Oktober 2024

Planlagt Fastgjort Låst Flyttet Genmab
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  • P Offline
    P Offline
    ProinvestorNEWS
    wrote on sidst redigeret af
    #844

    Genmab kan se frem til øgede royalties fra Novartis, som slår forventningerne https://proinvestor.com/investornyt/1234109/genmab-kan-se-frem-til-ogede-royalties-fra-novartis-som-slar-forventningerne

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    • exitnuE Offline
      exitnuE Offline
      exitnu
      wrote on sidst redigeret af
      #845

      Godt nyt mht. Kesimpta ...

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #846

        novartis q3-2024-investor-presentation https://www.novartis.com/sites/novartis_com/files/q3-2024-investor-presentation.pdf

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        • O Offline
          O Offline
          Oduk
          wrote on sidst redigeret af
          #847

          God formiddag, Jeg husker at der var en der lagde et link op til H2H undersøgelsen ville være færdig i udgang af oktober, men er der nogle som ved hvor længe der plejer at gå før vi ser disse data? Umiddelbart ville jeg jo mene at de skal udgives med det samme, men er der nogle som kan be- eller afkræfte dette?

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          • G Offline
            G Offline
            gentogen
            wrote on sidst redigeret af
            #848

            "Primary completion" (som næsten altid er et estimat) betyder strengt taget ikke færdig en bestemt dato, men kan for eksempel betyde, at den sidste patient forventes behandlet på et givet tidspunkt. Det er meget forskelligt, hvor hurtigt efter data offentliggøres.

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            • G Offline
              G Offline
              gentogen
              wrote on sidst redigeret af
              #849

              Da 'primary data' under alle omstændigheder ikke er de endelige data, så tror jeg ikke, at der er nogen pligt til at offentliggøre dem

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              • G Offline
                G Offline
                gentogen
                wrote on sidst redigeret af
                #850

                Altså i al almindelighed. Her ved vi jo, at de kommer

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #851

                  Q3-2024-PFE-Earnings-Release Pizer Tivdak $34 (32 US, 2 international) https://s28.q4cdn.com/781576035/files/doc_financials/2024/q3/Q3-2024-PFE-Earnings-Release-Final.pdf

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #852

                    Exclusive: Genmab lines up T cell engager pact with Revitope Oncology https://endpts.com/exclusive-genmab-lines-up-t-cell-engager-pact-with-revitope/ https://www.revitope.com/

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #853

                      3 targets, Genmab pays $9mn upfront with potential milestones up to $600mn, solid tumors

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                      • B Offline
                        B Offline
                        bikube
                        wrote on sidst redigeret af
                        #854

                        Er Tivdak stadig kun i 3. line. ?

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #855

                          yes. and only US and since this summer Macau, (not yet in mainland China). i assume that is where the $
                          2mn international is from, or maybe off-label. EU and Japan submitted this year.

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #856

                            We are waiting to see if they will proceed with trials for head and neck cancer which was one of the goals for this year, but seems a bit less certain after a recent evasive
                            remark by Klimovsky

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #857

                              Where i first thought that maybe Pfizer would be less interested in furthere Tiso development, now it could certainly also be Genmab after the addition of the Profound bio portfolio. If they really think toxicity is less with those ADC's then it is with Tiso ,
                              it may be smart to invest the money there...

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #858

                                a few changes in the GEN1046 Safety Trial write up. Also completion dates delayed (again) by a year this time; I wonder, given that they already stopped recruiting early this year, could that mean that patients stay on the drug longer than expected? or how should we look at this? https://clinicaltrials.gov/study/NCT03917381?tab=history&a=35&b=36#version-content-panel

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                                • B Offline
                                  B Offline
                                  bikube
                                  wrote on sidst redigeret af
                                  #859

                                  Thanks E L.

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #860

                                    GEN1047 set to Active not recruiting at 179 actual patients vs 400 expected, so I guess that doesn't look good? Not a very big surprise , was expecting news this quarter, let's see if they can give an update next week
                                    https://clinicaltrials.gov/study/NCT05180474?tab=history&a=16&b=17#version-content-panel

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #861

                                      large new Amivantamab Ph3
                                      trial Versus Cetuximab as First-line Treatment in Participants With KRAS/​NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer (OrigAMI-2) https://clinicaltrials.gov/study/NCT06662786

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                                      • L Offline
                                        L Offline
                                        lahn1
                                        wrote on sidst redigeret af
                                        #862

                                        Tivdak er da godkendt i 2L cervical cancer med accelerate approval og 3 L SCCHN not ?

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #863

                                          sorry, i stand corrected, misread the question, approved 2L+, not yet in first line

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