Genmab — Juni 2023

[Solsen]

Lidt om Car-T https://endpts.com/new-car-t-data-look-spectacular-but-how-many-patients-will-take-it-and-when-asco23/

[E_L]

longer term results of patients with DLBCL treated with epcoritamab+R-CHOP. The latest results support the preliminary data and this treatment induces high CMR rates with a manageable safety profile https://twitter.com/lymphomahub/status/1666142892270682128

[Bulder]

Dansk begejstring over FDA-godkendelse af epcoritamab: Det er et stort fremskridt

[Bulder]

Dansk begejstring over FDA-godkendelse af epcoritamab: Det er et stort fremskridt

De amerikanske lægemiddelmyndigheder FDA har godkendt det bispecifikke antistof epcoritamab til behandling af patienter med relaps eller refraktært (r/r) storce

(haematologisktidsskrift.dk)

[Bulder]

God og grundig artikel, der belyser “styrkeforholdet” epco/glofi/car-t.

[Pensionisten]

Tak for den gode artikel, @Bulder. Den var til at forstå - selv for mig! Og det siger ikke så lidt

[E_L]

Epcoritamab Plus Rituximab/Lenalidomide Produces Responses in High-risk R/R Follicular Lymphoma https://www.onclive.com/view/epcoritamab-plus-rituximab-lenalidomide-produces-responses-in-high-risk-r-r-follicular-lymphoma (this was the oral presentation)

[E_L]

Epcoritamab + R2 regimen and responses in high-risk follicular lymphoma, regardless of POD24 status. https://ascopubs.org/doi/abs/10.1200/JCO.2023.41.16_suppl.7506?af=R

[E_L]

so the first article is the new/later cutoff date of January 31, 2023; results very similar

[E_L]

104 efficacy evaluable patients treated with epcoritamab at 48 mg plus R2, the overall response rate (ORR) was 98% (median follow-up, 11.4 months). The complete metabolic response (CMR) was
87%

[E_L]

(versus the the immediate prior therapy they progressed on,
85% and 58% respectively)

[E_L]

easier article maybe - Positive Responses Seen in Follicular Lymphoma When Epcoritamab Is Added to Rituximab and Lenalidomide https://dailynews.ascopubs.org/do/positive-responses-seen-follicular-lymphoma-epcoritamab-added-rituximab-and

[Bulder]

As far as I remember Genmab was planning to file epco for approval in FL this year. But I don’t remember if it was RR or 1L. Do you?

[E_L]

oh good question, i had assumed RR as that is usually the case for a first approval
...

[Helge_LarsenPI-redaktør]

Godmorgen

[Stroka]

God morgen

[ProinvestorNEWS]

Shortpositioner på danske aktier https://www.proinvestor.com/boards/113022

[Klarussen]

Short Genmab stabil 0,43%, fint, fint. Og det gode ved shorts er jo at de skal købes tilbage på et tidspunkt som Buffet siger

[AaBforever]

Ja spændende hvornår turen op til 3500 starter...;-)

[Riis7]

Buffet køber ikke aktier unden udbytte og aktietilbagekøbs program:-) Genmabs aktietilbagekøbs program er kun til deres medarbejder:-)