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  4. Genmab — Juni 2023

Genmab — Juni 2023

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #94

    Jamen er det ikke hvad vi altid har sagt? Og når de så lægger dara oveni, så får vi ORR-rater på 105%. 🙂 Jeg tør slet ikke tænke på, hvad der vi når op på, når superdara kommer.

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    • B Offline
      B Offline
      bibob
      wrote on sidst redigeret af
      #95

      Fra ASCO. https://www.fiercebiotech.com/biotech/jjs-new-multiple-myeloma-combo-produces-deja-vu-96-carvykti-response?utm_medium=email&utm_source=nl&utm_campaign=LS-NL-FierceBiotech+Tracker&oly_enc_id=6900G6464778A3A

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      • B Offline
        B Offline
        bibob
        wrote on sidst redigeret af
        #96

        Sorry. Havde ikke set E L link 21.07 😉

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #97

          https://www.bt.dk/udland/nyt-studie-overrasker-pille-halverer-risikoen-for-at-doe-af-lungekraeft Osimertinib vækker opsigt. Amivantamab går efter det marked (Tagrisso) i kombi med Lazertinib.

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          • P Offline
            P Offline
            Pensionisten
            wrote on sidst redigeret af
            #98

            Fireside Goldman Sachs - desværre ikke Jan, der deltager (link)

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            • P Offline
              P Offline
              Pensionisten
              wrote on sidst redigeret af
              #99

              https://ir.genmab.com/genmab-news#content

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #100

                Wainwright analyst Ram Selvaraju reiterated a Buy rating on Genmab (GMAB – Research Report) today and set a price target of $51.00.

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                • K Offline
                  K Offline
                  Klarussen
                  wrote on sidst redigeret af
                  #101

                  Lyder meget rimeligt

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                  • B Offline
                    B Offline
                    bikube
                    wrote on sidst redigeret af
                    #102

                    Den 22. maj hævede han fra 47 til 51. Det svarer til lidt over 3500 i DK.

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                    • SolsenS Offline
                      SolsenS Offline
                      Solsen
                      wrote on sidst redigeret af
                      #103

                      Lidt om Car-T https://endpts.com/new-car-t-data-look-spectacular-but-how-many-patients-will-take-it-and-when-asco23/

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #104

                        longer term results of patients with DLBCL treated with epcoritamab+R-CHOP. The latest results support the preliminary data and this treatment induces high CMR rates with a manageable safety profile https://twitter.com/lymphomahub/status/1666142892270682128

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #105

                          Dansk begejstring over FDA-godkendelse af epcoritamab: Det er et stort fremskridt

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #106

                            Link Preview Image
                            Dansk begejstring over FDA-godkendelse af epcoritamab: Det er et stort fremskridt

                            De amerikanske lægemiddelmyndigheder FDA har godkendt det bispecifikke antistof epcoritamab til behandling af patienter med relaps eller refraktært (r/r) storce

                            favicon

                            (haematologisktidsskrift.dk)

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #107

                              God og grundig artikel, der belyser “styrkeforholdet” epco/glofi/car-t.

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                              0
                              • P Offline
                                P Offline
                                Pensionisten
                                wrote on sidst redigeret af
                                #108

                                Tak for den gode artikel, @Bulder. Den var til at forstå - selv for mig! Og det siger ikke så lidt 😉

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #109

                                  Epcoritamab Plus Rituximab/Lenalidomide Produces Responses in High-risk R/R Follicular Lymphoma https://www.onclive.com/view/epcoritamab-plus-rituximab-lenalidomide-produces-responses-in-high-risk-r-r-follicular-lymphoma (this was the oral presentation)

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #110

                                    Epcoritamab + R2 regimen and responses in high-risk follicular lymphoma, regardless of POD24 status. https://ascopubs.org/doi/abs/10.1200/JCO.2023.41.16_suppl.7506?af=R

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #111

                                      so the first article is the new/later cutoff date of January 31, 2023; results very similar

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #112

                                        104 efficacy evaluable patients treated with epcoritamab at 48 mg plus R2, the overall response rate (ORR) was 98% (median follow-up, 11.4 months). The complete metabolic response (CMR) was
                                        87%

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #113

                                          (versus the the immediate prior therapy they progressed on,
                                          85% and 58% respectively)

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