Genmab — November 2020

Helge_LarsenPI-redaktør

God morgen.

Helge_LarsenPI-redaktør

Asien: Fremgang til de fleste markeder - teknologi dykkerhttps://www.proinvestor.com/investornyt/669491/asien-fremgang-til-de-fleste-markeder-teknologi-dykker

Helge_LarsenPI-redaktør

38.000 medlemmer i nat. https://www.facebook.com/groups/1552522675046712

Helge_LarsenPI-redaktør

Vores Genmabgruppe passerede 3.000 medlemmer https://www.facebook.com/groups/1814736572095032

deleted-user

Flot Helge! Det gør kursen på Genmab også snart Godmorgen til jer alle

Solsen

HSCB løfter til 1510. Gad vide hvad de laver i den bank. Har været helt til grin gennem mange år.

Helge_LarsenPI-redaktør

Aktier/tendens: Ambu skuffer og Bavarian løfter på stor regnskabsdaghttps://www.proinvestor.com/investornyt/669501/aktier-tendens-ambu-skuffer-og-bavarian-lofter-pa-stor-regnskabsdag

JørgenVarnæs

33k warrants udnyttet til under kurs 100 - mon ikke vi kommer til at se noget skattedrevet udsalg i løbet af dagen i dag?

AaBforever

Tror jeg...ny dag truer..

E_L

BioNTech SE (BNTX) Q3 2020 Earnings Call Transcript https://www.fool.com/earnings/call-transcripts/2020/11/11/biontech-se-bntx-q3-2020-earnings-call-transcript/

E_L

worth having a look, a bit more on GEN1046 as i had expected -BNT311

E_L

so it was at the press briefing of
SITC yesterday

E_L

data was only three months median follow-up, putting more perspective on how early the data really is and why they are pleased with it

E_L

"Conditional activation of 4-1BB is crucial as clinical development of 4-1BB agonist has been hampered by severe liver toxicity." and later on "the reason for reduced liver toxicity is the conditional binding mechanism to 4-1BB, which means that the antibody has to be bound to PD-L1 in order to be able to bind to 4-1BB by a confirmational change"

E_L

that clarifies the liver tox issue a bit better to me, or should i say, the reason they expect less toxicity

GeorgeBest

Great E L

Bulder

Good, thx E L

Bulder

Our Genmab colleagues and we are considering these results as encouraging.

JørgenVarnæs

Nice one EL - definitely a thing to watch closely

E_L

I was a bit surprised by the low Ph 2 dose though? "what dose was selected for dose expansion for 1046 or 311 in non-small cell, please? -> The second question was what our recommended Phase 2 dose is. This will be 100 milligrams."