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Genmab — Maj 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • G Offline
    G Offline
    GeorgeBest
    wrote on sidst redigeret af
    #68

    Fed overskift på Blood artikel: AL patients don’t dare go without dara (artiklen i Rajkumars tweet) https://twitter.com/vincentrk/status/1256213766628347907?s=21

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    • G Offline
      G Offline
      GeorgeBest
      wrote on sidst redigeret af
      #69

      Congratulations to Genmab, @LUMC_Leiden, @MedicineUVA and @VUmcAmsterdam team on getting published in the Blood Cancer Journal. The study shares insight on potent anti-tumor activity exhibited by DuoHexaBody-CD37® in preclinical B-cell malignancy models. https://twitter.com/genmab/status/1256252129792217090?s=21

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      • M Offline
        M Offline
        Mcjean
        wrote on sidst redigeret af
        #70

        godkendt i US ?

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        • M Offline
          M Offline
          Mcjean
          wrote on sidst redigeret af
          #71

          yep

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          • K Offline
            K Offline
            KWC
            wrote on sidst redigeret af
            #72

            Genmab Announces U.S. FDA Approval of Subcutaneous Formulation of Daratumumab, DARZALEX FASPRO™ (daratumumab and hyaluronidase-fihj), for the Treatment of Patients with Multiple Myeloma
            Company Announcement

            Subcutaneous formulation of daratumumab, DARZALEX FASPRO™, approved by the U.S. FDA for the treatment of patients with multiple myeloma
            Approval based on data from Phase III COLUMBA and Phase II PLEIADES studies
            In the studies, the fixed-dose subcutaneous formulation reduced treatment time

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #73

              https://ir.genmab.com/news-releases/news-release-details/genmab-announces-us-fda-approval-subcutaneous-formulation

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              • PederTP Offline
                PederTP Offline
                PederT
                wrote on sidst redigeret af
                #74

                Sådan ????

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                • PederTP Offline
                  PederTP Offline
                  PederT
                  wrote on sidst redigeret af
                  #75

                  Chatten er åbenbart ikke optimeret til til emojis 😉 Fedt med den nyhed en fredag aften. Cheers to that!

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                  • BudweisB Offline
                    BudweisB Offline
                    Budweis
                    wrote on sidst redigeret af
                    #76

                    Bingo!

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #77

                      Godkendelsen er specifik. Alcyone, Maia, Castor og Pollux samt monoterapi. Dvs i princippet ikke gældende i transplant-setting: Griffin.

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                      • O Offline
                        O Offline
                        OHW
                        wrote on sidst redigeret af
                        #78

                        Ikke den store reaktion i US. Kun delvis godkendelse?

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #79

                          Delvis og delvis. Godkendelsen dækker de felter, hvor dara i forvejen er godkendt. Men der skal måske en ny ansøgning til for at få den godkendt i DRVd-kombinationen (asct-setting).

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #80

                            Som jeg læser det dækker godkendelsen også dara-pom-dex i 3. linje.

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #81

                              Formuleringen, "patients with relapsed or refractory multiple myeloma who have received at least one prior therapy", rummer både Pollux og dara-pom-dex.

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #82

                                Formuleringen "in combination with bortezomib and dexamethasone in patients who have received at least one prior therapy" går specifikt på Castor.

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                                • troldmandenT Offline
                                  troldmandenT Offline
                                  troldmanden
                                  wrote on sidst redigeret af
                                  #83

                                  skøn fredag. Men lidt som ventet ikke den store reaktion da det netop vr ventet. Læser jeg det rigtigt at det så ikke er 1. line

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                                  • V Offline
                                    V Offline
                                    Vitus
                                    wrote on sidst redigeret af
                                    #84

                                    Pensionisten: Du skal da ha en ny IPad 🙂

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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #85

                                      Tillykke med sc approval

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                                      • V Offline
                                        V Offline
                                        Vitus
                                        wrote on sidst redigeret af
                                        #86

                                        Nå for Søren...ja så er der noget andet galt 🙂

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                                        0
                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #87

                                          🙂

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