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Genmab — Maj 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • G Offline
    G Offline
    GeorgeBest
    wrote on sidst redigeret af
    #63

    Patienthistorien og kommentarer til Amivantamab (18:26) er interessant. Noget giftigt stads, men disse patienter har vist ikke mange andre muligheder...

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    • A Offline
      A Offline
      AaBforever
      wrote on sidst redigeret af
      #64

      Vitus... afkast på mine bull´s i år til dato...kom ud inden den crashed og ind igen på det rigtige tidspunkt...ved ikke om det er mere held end forstand..:-D

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      • A Offline
        A Offline
        AaBforever
        wrote on sidst redigeret af
        #65

        Jeg daytrader...

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        • A Offline
          A Offline
          AaBforever
          wrote on sidst redigeret af
          #66

          Måske...men det sidste halve år er det gået meget godt...:-)

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          • A Offline
            A Offline
            AaBforever
            wrote on sidst redigeret af
            #67

            Jeg har mine laaange Genmab som bare står..det andet er noget jeg leger lidt med;-)

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #68

              Fed overskift på Blood artikel: AL patients don’t dare go without dara (artiklen i Rajkumars tweet) https://twitter.com/vincentrk/status/1256213766628347907?s=21

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              • G Offline
                G Offline
                GeorgeBest
                wrote on sidst redigeret af
                #69

                Congratulations to Genmab, @LUMC_Leiden, @MedicineUVA and @VUmcAmsterdam team on getting published in the Blood Cancer Journal. The study shares insight on potent anti-tumor activity exhibited by DuoHexaBody-CD37® in preclinical B-cell malignancy models. https://twitter.com/genmab/status/1256252129792217090?s=21

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                • M Offline
                  M Offline
                  Mcjean
                  wrote on sidst redigeret af
                  #70

                  godkendt i US ?

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                  • M Offline
                    M Offline
                    Mcjean
                    wrote on sidst redigeret af
                    #71

                    yep

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                    • K Offline
                      K Offline
                      KWC
                      wrote on sidst redigeret af
                      #72

                      Genmab Announces U.S. FDA Approval of Subcutaneous Formulation of Daratumumab, DARZALEX FASPRO™ (daratumumab and hyaluronidase-fihj), for the Treatment of Patients with Multiple Myeloma
                      Company Announcement

                      Subcutaneous formulation of daratumumab, DARZALEX FASPRO™, approved by the U.S. FDA for the treatment of patients with multiple myeloma
                      Approval based on data from Phase III COLUMBA and Phase II PLEIADES studies
                      In the studies, the fixed-dose subcutaneous formulation reduced treatment time

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                      • G Offline
                        G Offline
                        GeorgeBest
                        wrote on sidst redigeret af
                        #73

                        https://ir.genmab.com/news-releases/news-release-details/genmab-announces-us-fda-approval-subcutaneous-formulation

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                        • PederTP Offline
                          PederTP Offline
                          PederT
                          wrote on sidst redigeret af
                          #74

                          Sådan ????

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                          • PederTP Offline
                            PederTP Offline
                            PederT
                            wrote on sidst redigeret af
                            #75

                            Chatten er åbenbart ikke optimeret til til emojis 😉 Fedt med den nyhed en fredag aften. Cheers to that!

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                            • BudweisB Offline
                              BudweisB Offline
                              Budweis
                              wrote on sidst redigeret af
                              #76

                              Bingo!

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #77

                                Godkendelsen er specifik. Alcyone, Maia, Castor og Pollux samt monoterapi. Dvs i princippet ikke gældende i transplant-setting: Griffin.

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                                • O Offline
                                  O Offline
                                  OHW
                                  wrote on sidst redigeret af
                                  #78

                                  Ikke den store reaktion i US. Kun delvis godkendelse?

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #79

                                    Delvis og delvis. Godkendelsen dækker de felter, hvor dara i forvejen er godkendt. Men der skal måske en ny ansøgning til for at få den godkendt i DRVd-kombinationen (asct-setting).

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #80

                                      Som jeg læser det dækker godkendelsen også dara-pom-dex i 3. linje.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #81

                                        Formuleringen, "patients with relapsed or refractory multiple myeloma who have received at least one prior therapy", rummer både Pollux og dara-pom-dex.

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #82

                                          Formuleringen "in combination with bortezomib and dexamethasone in patients who have received at least one prior therapy" går specifikt på Castor.

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