Genmab — Marts 2020
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Vincent Rajkumar
@VincentRK
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7 t
Today @US_FDA
@FDAOncology
approved isatuximab (Sarclisa) for relapsed refractory myeloma.Im happy that @SanofiUS
has priced it significantly lower than daratumumab. I hope there is a price war, & prices drop more. Based on cost, I’ll prefer Isa-PomDex to Dara-PomDex. @mtmdphd -
Vincent Rajkumar
@VincentRK
·
7 t
I was an author on the isatuximab pivotal trial. Im working with both @sanofi
and @JanssenUS
on other trials.Look forward to thoughts on how we support the appropriate choice of drug taking cost into account from @Rfonsi1
@akeithstewart
@peterbachmd
& others who are interested -
#ACTRIMS2020 – Results of Ofatumumab Self-injection Pen Equivalent to Infusion, APLIOS Trial Shows https://multiplesclerosisnewstoday.com/news-posts/2020/02/28/actrims2020-poster-session-lb300-onset-of-b-cell-depletion-with-subcutaneous-administration-of-ofatumumab-in-relapsing-multiple-sclerosis-results-from-the-aplios-bioequivalence-study
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Det største problem med Sanofi er, at pt sælger Genmab mest med Daratumumab i kombination med POM-DEX, så det er lidt samme patientgrundlag. Tilsyneladende er denne kombi ogås meget brugt i anden linie, så spørgsmålet er om Sanofi også kan vinde indpas der med en lavere prissætning. Lad os håbe at sc dosering er en game changer som Jan siger - omvendt kan Sanofi indpas gøre det svært for JNJ at hæve prisen pt.
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I agreed E L.
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Har Karyopharm - spændende hvor markedet reagrer ovenpå den stigning i går. Og så LIGE efter melder ud at de skal hente penge... Smart timing
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The U.S. list price (wholesale acquisition cost, or WAC) for Sarclisa is $650 per 100 mg vial and $3,250 per 500 mg vial. For a typical patient in the U.S., between 70-80 kg (154-176 lbs), this correlates to a cost of $5,200 per infusion. Actual costs to patients are generally anticipated to be lower as the list price does not reflect insurance coverage, copay support, or financial assistance from patient support programs.
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