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Genmab — Juni 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #947

    a few more CASSIOPEIA slides https://twitter.com/MM_Hub/status/1139912006511800320

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #948

      ADCT-301
      https://twitter.com/graham74GC/status/1139849029637083136

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      0
      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #949

        Just a moment...

        favicon

        (onlinelibrary.wiley.com)

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #950

          Impressive responses - hope sideeffects are acceptable. 3 CR after discontinuation are also impressive. Thanks EL !

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #951

            ANDROMEDA looks very good too !

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            • M Offline
              M Offline
              mobbyduck1
              wrote on sidst redigeret af
              #952

              ANDROMEDA looks fantastic, how can
              we ask for more??

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              0
              • T Offline
                T Offline
                transalp
                wrote on sidst redigeret af
                #953

                WAAUH.. ANDROMEDA..

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                • nohopeN Offline
                  nohopeN Offline
                  nohope
                  wrote on sidst redigeret af
                  #954

                  Føler jeg går glip af et eller andet....

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                  0
                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #955

                    Angående BergenBio så er jeg også sikker på at faldet primært skyldes emissionen:

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                    0
                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #956

                      NewsWeb

                      favicon

                      (newsweb.oslobors.no)

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                      0
                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #957

                        Man kan mene hvad man vil om forløbet (og ja jeg er ikke begejstret), men nu bør der ligge en bund i 13,50.

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #958

                          Tolero kommer med data fra deres AXL inhibitor på EHA og præsenterede også flotte data i AML med deres CDK9 inhibitor:

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                          0
                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #959

                            Just a moment...

                            favicon

                            (www.firstwordpharma.com)

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                            • B Offline
                              B Offline
                              bibob
                              wrote on sidst redigeret af
                              #960

                              Mere AML. https://www.onclive.com/conference-coverage/eha-2019/new-macrophage-immune-checkpoint-strategy-shows-promise-in-aml-and-mds

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #961

                                Tak, bibob. Mere makrofag-aktivering. Lidt anderledes virkemåde end dara-cyclo i MM, som vi så forleden, men resultatet er det samme.

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #962

                                  Der kører allerede et studie med dara i kombi med azaciditin (og SY-1425) i AML og MDS. https://clinicaltrials.gov/ct2/show/NCT02807558?term=daratumumab+aml&rank=3

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #963

                                    Så vi kommer nok til at høre mere om vore venner, makrofagerne.

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                                    0
                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #964

                                      Spørgsmålet er så om Hu5F9-G4 er mere effektivt end dara i så henseende, da det direkte binder sig til CD47, som er et makrofag hæmmende checkpoint.

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                                      • B Offline
                                        B Offline
                                        bibob
                                        wrote on sidst redigeret af
                                        #965

                                        Spørgsmålet er vel også om hvem der er først med et drug der er effektivt. Kunne være rart at være nr 1 på banen.

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                                        • B Offline
                                          B Offline
                                          bibob
                                          wrote on sidst redigeret af
                                          #966

                                          God morgen. :-).

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                                          0

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