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Genmab — Juni 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #946

    ANDROMEDA https://twitter.com/MM_Hub/status/1139913117272555520

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #947

      a few more CASSIOPEIA slides https://twitter.com/MM_Hub/status/1139912006511800320

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      0
      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #948

        ADCT-301
        https://twitter.com/graham74GC/status/1139849029637083136

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #949

          Just a moment...

          favicon

          (onlinelibrary.wiley.com)

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #950

            Impressive responses - hope sideeffects are acceptable. 3 CR after discontinuation are also impressive. Thanks EL !

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            • SolsenS Offline
              SolsenS Offline
              Solsen
              wrote on sidst redigeret af
              #951

              ANDROMEDA looks very good too !

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              • M Offline
                M Offline
                mobbyduck1
                wrote on sidst redigeret af
                #952

                ANDROMEDA looks fantastic, how can
                we ask for more??

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                0
                • T Offline
                  T Offline
                  transalp
                  wrote on sidst redigeret af
                  #953

                  WAAUH.. ANDROMEDA..

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                  0
                  • nohopeN Offline
                    nohopeN Offline
                    nohope
                    wrote on sidst redigeret af
                    #954

                    Føler jeg går glip af et eller andet....

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                    0
                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #955

                      Angående BergenBio så er jeg også sikker på at faldet primært skyldes emissionen:

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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #956

                        NewsWeb

                        favicon

                        (newsweb.oslobors.no)

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                        0
                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #957

                          Man kan mene hvad man vil om forløbet (og ja jeg er ikke begejstret), men nu bør der ligge en bund i 13,50.

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                          0
                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #958

                            Tolero kommer med data fra deres AXL inhibitor på EHA og præsenterede også flotte data i AML med deres CDK9 inhibitor:

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                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #959

                              Just a moment...

                              favicon

                              (www.firstwordpharma.com)

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                              • B Offline
                                B Offline
                                bibob
                                wrote on sidst redigeret af
                                #960

                                Mere AML. https://www.onclive.com/conference-coverage/eha-2019/new-macrophage-immune-checkpoint-strategy-shows-promise-in-aml-and-mds

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #961

                                  Tak, bibob. Mere makrofag-aktivering. Lidt anderledes virkemåde end dara-cyclo i MM, som vi så forleden, men resultatet er det samme.

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #962

                                    Der kører allerede et studie med dara i kombi med azaciditin (og SY-1425) i AML og MDS. https://clinicaltrials.gov/ct2/show/NCT02807558?term=daratumumab+aml&rank=3

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #963

                                      Så vi kommer nok til at høre mere om vore venner, makrofagerne.

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #964

                                        Spørgsmålet er så om Hu5F9-G4 er mere effektivt end dara i så henseende, da det direkte binder sig til CD47, som er et makrofag hæmmende checkpoint.

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                                        • B Offline
                                          B Offline
                                          bibob
                                          wrote on sidst redigeret af
                                          #965

                                          Spørgsmålet er vel også om hvem der er først med et drug der er effektivt. Kunne være rart at være nr 1 på banen.

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                                          0

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