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Genmab — Juni 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #3

    @peter12: Det kan minde om car-t, idet man udtager T-celler fra pt, mangfoldiggør dem, og genindsætter. Så vidt jeg kan forstå udtager man kun de T-celler, der allerede kan genkende tumor-cellerne, så man ikke skal "omprogrammere" som i car-t. https://www.iovance.com/clinical/c-145-04-cervical-carcinoma/

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    • Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktør
      wrote on sidst redigeret af
      #4

      Tak GB...Jeg bemærkede især:
      Andrew Yee, MD
      ‏ @andrew02114
      31. maj

      "
      I’ve been using both, haven’t committed to one regimen versus the other! RVD lite is very easy to give, though depth of response with dara Rd especially in standard risk is impressive and no real risk of peripheral neuropathy".

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      • D Offline
        D Offline
        DevOp
        wrote on sidst redigeret af
        #5

        Fedt GB, det var da lige MAIA-resultater fra nejm, der var linket til (har ikke set andet link til dem), med estimeret 30 måneders PFS for Dara-combi på 70,6% vs. 55,6% i control group og som set tidligere en væsetlig dybere respons med 47,6% CR or better i dara-combi vs. 24,9% i control group. direkte link https://www.nejm.org/doi/full/10.1056/NEJMoa1817249

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        • Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktør
          wrote on sidst redigeret af
          #6

          Hej DevOp...Vi havde linket oppe og vende i går.

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #7

            Sorry i forgårs 8,21 og 9,41.

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #8

              JNJ-372 https://twitter.com/Jbauml/status/1134526398360670209 or more via search https://twitter.com/search?q=JNJ-372&src=typed_query&f=live

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              • J Offline
                J Offline
                jkj
                wrote on sidst redigeret af
                #9

                Is JNJ-372 the same as JNJ-61186372 E L ?

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #10

                  yes

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                  • G Offline
                    G Offline
                    GeorgeBest
                    wrote on sidst redigeret af
                    #11

                    JNJ-372 looks very promissing according this. But the other day there were statements that efficiacy was not overwhelming! What should believe in?

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                    • D Offline
                      D Offline
                      DevOp
                      wrote on sidst redigeret af
                      #12

                      De var smuttet. Men det ser da i det mindste rigtig godt ud - ligner lidt samme billede, vi har set tidligere med dybere respons og større forskel ift control group, jo længere tid, der går

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                      • P Offline
                        P Offline
                        peter12
                        wrote on sidst redigeret af
                        #13

                        @GB believe facts (what you see) and not what some people say. If J&J see a blockbuster I believe it though 😉

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                        0
                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #14

                          GB if it was Ohad Hammer then he is very hard to impress so dont worry

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                          0
                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #15

                            OK thanks Sukkeralf and peter12. I will stop worrying 🙂

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                            • M Offline
                              M Offline
                              Monforte
                              wrote on sidst redigeret af
                              #16

                              @Bulder 9:34, nej var med i fase II-studiet fra juni 2014
                              og stoppede i marts 2016 med Rd

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                              0
                              • J Offline
                                J Offline
                                jkj
                                wrote on sidst redigeret af
                                #17

                                intet at finde nogen steder om dagens fremlæggelser fra Genmab.

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                                • G Offline
                                  G Offline
                                  GeorgeBest
                                  wrote on sidst redigeret af
                                  #18

                                  Der er i morgen jkj https://twitter.com/janssenus/status/1134882324125032450?s=21

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #19

                                    Prof Maria-Victoria Mateos talks to ecancer at
                                    2019 ASCO about the COLOMBA study into subcutaneous versus intravenous dara https://ecancer.org/video/7904/subcutaneous-versus-intravenous-daratumumab-administration-in-patients-with-relapsed-or-refractory-multiple-myeloma.php

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                                    • G Offline
                                      G Offline
                                      GeorgeBest
                                      wrote on sidst redigeret af
                                      #20

                                      Myeloma. Skyrocketing drug prices https://twitter.com/rfonsi1/status/1134987324377501697?s=21

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #21

                                        @Tandfeen-2 Cassiopeia would indeed be the 1st frontline transplant eligable combi, admittedly mostly a european regimen though i think. Next will be Griffin , Dara + VRd, we should get 1st data soon, but i think that is a year behind Cassiopeia

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #22

                                          https://twitter.com/Mohty_EBMT/status/1134943201171824640

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                                          0

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