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Genmab — April 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • StockBullS Offline
    StockBullS Offline
    StockBull
    wrote on sidst redigeret af
    #423

    Kommer der lıdt mere focus paa pıpelınen og en stor partneraftale saa tror jeg faktısk godt Genmab kan rykke op omkrıng PE 60 ıgen og saa vıl kursen sparke roev 🙂

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    • StockBullS Offline
      StockBullS Offline
      StockBull
      wrote on sidst redigeret af
      #424

      selvfoelgelıg kombıneret med gode ( lıdt bedre end konsensus) salgstal

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #425

        Celebrating 20 Years http://www.genmab.com/careers/celebrating-20-years

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #426

          the Technology appraisal guidance [by NICE was published , where you can see how they got to their decision in plain language https://www.nice.org.uk/guidance/ta573/chapter/Recommendations

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #427

            Amgen is still working on this Anti-CD38/CD3 Bispecific T Cell-Recruiting Antibody ( https://www.ncbi.nlm.nih.gov/pubmed/30918018 ) ; just out of
            interest, does anyone know if Genmab would still be allowed to work on duo or hexa bodies including CD38? or is this excluded via the JNJ dara deal?

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #428

              I think Jan have been asked these kind of questions before - and his answer was that ADC is not the way forward and when you something that works that well as dara does its better to go after other targets........and thats what Janssen does. So I dont think its relevant

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              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #429

                That should maybe be hexaboost as life cicle management

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #430

                  well, yes, that would be an interesting development; are you thinking a HexaDara to increase patent life and some extra Hexa licencing money? I like it 😉

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #431

                    Well, the question was about bispecifics. Genmab has out-licensed Daratumumab, not CD38. So I would guess that Genmab is free to pursue CD38 as any other company is.

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                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #432

                      But I thin the main problem is that Dara is so good that its hard to compete.........and when you get to the market you will maybe soon face dara without patent protection

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #433

                        true. I was just thinking how it could completely change the relationship with JNJ if Genmab could develop an improved duo or hexa. but i guess it is more a hypothetical question

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #434

                          it sure would change the perspective on a take-over 😉

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #435

                            Im sure they cant use dara for that - and dara was a quite unique antibody found among 70 or 90 antibodies they maked against CD38. So the problem would also be that they probably should use an less optimal antibody and then you behind from the beginning.

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #436

                              They already have the bcma x cd3 duo in MM going with Janssen. So they'll probably stick to that. Is a hex cd38 possible?

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #437

                                In the early days Genmab presented CD38 hexaboosted - but the was not dara if I remember correctly - and dara already has good CDC

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #438

                                  and GPRC5D bispecific with Janssen

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                                  • P Offline
                                    P Offline
                                    peter12
                                    wrote on sidst redigeret af
                                    #439

                                    Billig Revlimid i US allerede fra marts 2022 ? https://www.alvogen.com/newsroom/alvogen-settles-u-s-revlimid-r-patent-litigation-with-celgene

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #440

                                      Umiddelbart har Sanofi et samarbejde med Elektrofi - kan dog ikke rigtig finde noget om samarbejdet, men måske det kunne være for at få isatuximab som sc dosering

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                                      • S Offline
                                        S Offline
                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #441

                                        Link Preview Image
                                        Halozyme

                                        favicon

                                        Halozyme (www.elektrofi.com)

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                                        • J Offline
                                          J Offline
                                          JohnW
                                          wrote on sidst redigeret af
                                          #442

                                          Kom nu, Maia!

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