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Genmab — Januar 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • Legolas23L Offline
    Legolas23L Offline
    Legolas23
    wrote on sidst redigeret af
    #487

    Kan man ikke anvende RTOR på SQ ?

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    • P Offline
      P Offline
      Plimsoller
      wrote on sidst redigeret af
      #488

      @Legolas
      Det blev diskuteret her på chatten for et godt stykke tid, og det var der delte meninger om.

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      0
      • T Offline
        T Offline
        Tandfeen-2
        wrote on sidst redigeret af
        #489

        Så begriber jeg ikke deres kursmål på 1050

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        • Legolas23L Offline
          Legolas23L Offline
          Legolas23
          wrote on sidst redigeret af
          #490

          Jeg fulgte de godt, og jeg spørger igen, fordi jeg lige så @Bulder online. Man må antage med en rigtig god dialog med FDA at RTOR ikke lå særlig langt væk. Vi få nok ikke et klart svar, men vi må gisne her på siden og i baglandet.

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          • P Offline
            P Offline
            Plimsoller
            wrote on sidst redigeret af
            #491

            Ok. Ja jeg ved det bestemt ikke. Kan blot håbe.

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            • StockBullS Offline
              StockBullS Offline
              StockBull
              wrote on sidst redigeret af
              #492

              Ved ikke om SC kommer på marked i 2019 men bare det der kommer positiv data kan vel få kursen til at rykke for så er 2020 og 4.5 mia i dara
              salg 99% sikker

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              • StockBullS Offline
                StockBullS Offline
                StockBull
                wrote on sidst redigeret af
                #493

                samt vejen op til 10 mia usd er lagt, så er det bare op til sælgerne

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                • G Offline
                  G Offline
                  gentogen
                  wrote on sidst redigeret af
                  #494

                  OM RTOR hedder det, at "Supplements with CMC formulation changes and supplements with pharmacology/toxicology data will be excluded." jeg er langt fra ekspert i terminologien , men gætter vel lidt på, at det omfatter SQ

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                  • StockBullS Offline
                    StockBullS Offline
                    StockBull
                    wrote on sidst redigeret af
                    #495

                    vis kursmål ? Tandfeen, JPM er på 1150 og de opjustere vel når RTOR og SC er igennem nåleøjet

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                    • StockBullS Offline
                      StockBullS Offline
                      StockBull
                      wrote on sidst redigeret af
                      #496

                      JPM forventer MAIA begunder at sælge i August 2019 og ser RTOR som en joker der kan give target et hak opad

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #497

                        Joker? - Snarere spar 5, der som bekendt rydder bordet 😉

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                        • StockBullS Offline
                          StockBullS Offline
                          StockBull
                          wrote on sidst redigeret af
                          #498

                          2019 guidance could have a degree of conservatism given
                          recent results
                          The key guidance metric the market is focused on is Darzalex in-market sales. There
                          is a focus on earnings and operating profit by some investors; however, given that
                          Genmab are building a pipeline for future value creation we do not believe investors
                          should be too focused on 2019 operating profit. Heading into 2019 we expect
                          Genmab to guide for Darzalex in market sales of $2.8-3.1bn, factoring in the launch of MAIA although

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                          • StockBullS Offline
                            StockBullS Offline
                            StockBull
                            wrote on sidst redigeret af
                            #499

                            also including the possibility of any potential price adjustment exUS. We forecast Darzalex sales of $3.1bn which is broadly in line with consensus of
                            $3.09bn. We expect guidance for revenue of DKr3,400-3,800m and Operating profit
                            of DKr1,600-1,800m. Our estimates are towards the top end of this range, with
                            consensus slightly above the top end of the range. Consensus appears to factor in
                            c.$50m more milestones in FY19; however ,with Darzalex forecasts in line we do not
                            expect significant downsid

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                            • StockBullS Offline
                              StockBullS Offline
                              StockBull
                              wrote on sidst redigeret af
                              #500

                              with the FY19 guidance in Feb'19.

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                              • StockBullS Offline
                                StockBullS Offline
                                StockBull
                                wrote on sidst redigeret af
                                #501

                                Consensus Comparison
                                Our 2018 revenue estimates are in line with Bloomberg consensus in 2018, although
                                we are ahead on Core Operating profit (5% ahead) as consensus is forecasting OpEx
                                towards the top end of the range vs. our assumption for the mid-point. We are
                                significantly ahead on EPS as we believe consensus misses the recognition of
                                deferred tax assets, which will wipe out the Q1-Q3 tax charge. In 2019 we are below
                                consensus (6%/DKr220m on the top line and 14%/DKr292m on Op Profit) as
                                conse

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #502

                                  @gentogen: "formulation changes" er vel netop når de tilsætter rhuph20?

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                                  • StockBullS Offline
                                    StockBullS Offline
                                    StockBull
                                    wrote on sidst redigeret af
                                    #503

                                    as
                                    consensus appears to factor in additional $50m in milestones vs. our estimates. In
                                    2020, we are broadly in line with consensus on the topline and operating profit, and
                                    below on net income – we assume consensus still has tax losses being utilised when
                                    we believe they will be fully utilised by 2020

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                                    • StockBullS Offline
                                      StockBullS Offline
                                      StockBull
                                      wrote on sidst redigeret af
                                      #504

                                      Risks to Rating and Price Target
                                      Downside risks include

                                      1. Darzalex misses consensus expectations due to competition from other antiCD38’s particularly isatuximab, which could lead to price declines,
                                        reducing Darzalex sales potential or lower-than-expected uptake.
                                      2. Stronger than expected competitor data which could threaten the position of
                                        Darzalex in frontline multiple myeloma.
                                      3. Failure to successfully develop a subcutaneous version of Darzalex, which could
                                        remove any of the advantages of c
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                                      • StockBullS Offline
                                        StockBullS Offline
                                        StockBull
                                        wrote on sidst redigeret af
                                        #505

                                        advantages of competitor CD38s over Darzalex and also
                                        fail to extend the patent life of Darzalex.
                                        Upside risks include

                                        1. We also see potential for upside from faster FDA approval of Darzalex in frontline
                                          Myeloma
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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #506

                                          Men det har efter min mening ikke den store betydning, hvornår sc kan godkendes. Hvis data viser det, vi forventer, så ryger kursen op, selvom salgseffekten først kommer ½ år senere.

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