Genmab — November 2018
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Man er klar over hvilke problemer, der er med CAR-t og arbejder naturligt nok med forbedringer https://ash.confex.com/ash/2018/webprogram/Paper119247.html
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Men havde analytikerne
ment at CAR-t ville snuppe en stor del af markedet, så ville de vel have skåret i topsalgsestimatet for Dara? -
Enig Solsen, men jeg undrer mig lidt over at de (på trods af CAR-t begejstringen), ikke decideret skærer ned på Dara topsalgsestimatet. Det giver ikke mening.
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Ofatumumab was active and safe in these elderly chemoimmunotherapy-treated patients with SMZL. IRRs were generally mild and easily manageable, even in a cohort of patients with a very high median age and a relevant comorbidity burden. The ORR and the CR rate compare favorably with data reported in the literature with rituximab monotherapy also considering that >75% of patients have been previously exposed to rituximab.
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this is what the genmab website says, http://www.genmab.com/product-pipeline/products-in-development/adct-301
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"While we have decided not to fund co-development of HuMax-TAC-ADC with ADC Therapeutics, we are pleased to still have 25% of the rights to the product, which has potential to become a first-in-class antibody-drug conjugate therapeutic in certain hematological cancer indications," said Jan van de Winkel, Ph.D., Chief Executive Officer of Genmab. https://ir.genmab.com/news-releases/news-release-details/genmab-retains-partial-rights-humax-tac-adc-will-not-exercise-co
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