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Genmab — Juli 2018

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • B Offline
    B Offline
    Bella1
    wrote on sidst redigeret af
    #891

    Fornemt og fortjent selskab! 🙂

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    • G Offline
      G Offline
      GeorgeBest
      wrote on sidst redigeret af
      #892

      Fin artikel om dara sc og amyloidosis (ANDROMEDA studiet) https://www.raredr.com/news/ray-comenzo-md-discusses-andromeda-trial-al-amyloidosis-patients

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      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #893

        "
        The response rates were really stunning even though these patients in the ramp-in didn’t go through the entire course of therapy before the responses were scored. They are still getting treated, obviously, but three-quarters of patients recorded very deep responses"

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        • Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktør
          wrote on sidst redigeret af
          #894

          "If daratumumab and CyBorD works better than CyBorD alone, we have a new standard of therapy for patients with light chain amyloidosis. In addition, the study is designed to allow patients to have their blood stem cells collected after 6 months of treatment"
          .

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #895

            Tak for link GB. 🙂

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            • Don_JoningD Offline
              Don_JoningD Offline
              Don_Joning
              wrote on sidst redigeret af
              #896

              den bed jeg også mærke i Helge 15.45 + "... 2 dozen patients were treated in the ramp-in, there was no safety problems with the subcutaneous daratumumab, and all of the 2 dozen patients received daratumumab with CyBorD.".

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              • J Offline
                J Offline
                JKY_VH
                wrote on sidst redigeret af
                #897

                Er der nogen der ved, hvor mange der er ramt af amyloidosis?

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                • Don_JoningD Offline
                  Don_JoningD Offline
                  Don_Joning
                  wrote on sidst redigeret af
                  #898

                  5/7 15:46
                  af gentogen
                  It is estimated that there are 12,000 adults in the United States currently living with AL amyloidosis. (Blood Cancer Journalvolume 8, Article number: 44 (2018)

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                  • G Offline
                    G Offline
                    GeorgeBest
                    wrote on sidst redigeret af
                    #899

                    har tidligere læst her at markedet for amyloidosis har en størrelses på ca. 20% af MM markedet

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                    • J Offline
                      J Offline
                      JKY_VH
                      wrote on sidst redigeret af
                      #900

                      Mange tak Don. Så vidt jeg kan forstå er sygdommen arvelig.

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                      • J Offline
                        J Offline
                        JKY_VH
                        wrote on sidst redigeret af
                        #901

                        og tak GB:-)

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                        • G Offline
                          G Offline
                          GeorgeBest
                          wrote on sidst redigeret af
                          #902

                          noget kunne tyde på at dara virker endnu bedre i amyloisosis end i MM

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                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #903

                            Kombinationen med CyBorD er også meget interessant i MM. Mener vi snart kan vente data.

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                            • B Offline
                              B Offline
                              bibob
                              wrote on sidst redigeret af
                              #904

                              Solsen. Resultater september. 18 . Men dog kun 18 patienter. If clinical trial. https://www.clinicaltrials.gov/ct2/show/NCT02955810?term=Dara%2BCyBorD&cond=MM&rank=1

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                              • SolsenS Offline
                                SolsenS Offline
                                Solsen
                                wrote on sidst redigeret af
                                #905

                                Der er også et fase 2 med 101 pts, der burde være data fra.

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #906

                                  https://www.clinicaltrials.gov/ct2/show/NCT02951819?term=Cybord&cond=Daratumumab&rank=3 8. marts 2018.

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #907

                                    Ser ud til at rekruttering stoppede marts og primary endpoint måles ved 4 mdr. Så vi nærmer os.

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #908

                                      new country, Panama - Aprueban nuevo tratamiento para el Mieloma Múltiple en Panamá - https://www.tvn-2.com/nacionales/salud/Aprueban-tratamiento-Mieloma-Multiple-Panama_0_5079991985.html

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #909

                                        161 to go @bibob ? 😉

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                                        • M Offline
                                          M Offline
                                          MarsFars
                                          wrote on sidst redigeret af
                                          #910

                                          Der kommer snart en lind strøm af nyheder om dara
                                          , eller? Håber de bliver dominerende gode

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