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Genmab — Juli 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktør
    wrote on sidst redigeret af
    #890

    Just a moment...

    favicon

    (www.proinvestor.com)

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    • B Offline
      B Offline
      Bella1
      wrote on sidst redigeret af
      #891

      Fornemt og fortjent selskab! 🙂

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      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #892

        Fin artikel om dara sc og amyloidosis (ANDROMEDA studiet) https://www.raredr.com/news/ray-comenzo-md-discusses-andromeda-trial-al-amyloidosis-patients

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        • Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktørH Offline
          Helge_LarsenPI-redaktør
          wrote on sidst redigeret af
          #893

          "
          The response rates were really stunning even though these patients in the ramp-in didn’t go through the entire course of therapy before the responses were scored. They are still getting treated, obviously, but three-quarters of patients recorded very deep responses"

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #894

            "If daratumumab and CyBorD works better than CyBorD alone, we have a new standard of therapy for patients with light chain amyloidosis. In addition, the study is designed to allow patients to have their blood stem cells collected after 6 months of treatment"
            .

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            • Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktør
              wrote on sidst redigeret af
              #895

              Tak for link GB. 🙂

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              • Don_JoningD Offline
                Don_JoningD Offline
                Don_Joning
                wrote on sidst redigeret af
                #896

                den bed jeg også mærke i Helge 15.45 + "... 2 dozen patients were treated in the ramp-in, there was no safety problems with the subcutaneous daratumumab, and all of the 2 dozen patients received daratumumab with CyBorD.".

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                • J Offline
                  J Offline
                  JKY_VH
                  wrote on sidst redigeret af
                  #897

                  Er der nogen der ved, hvor mange der er ramt af amyloidosis?

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                  • Don_JoningD Offline
                    Don_JoningD Offline
                    Don_Joning
                    wrote on sidst redigeret af
                    #898

                    5/7 15:46
                    af gentogen
                    It is estimated that there are 12,000 adults in the United States currently living with AL amyloidosis. (Blood Cancer Journalvolume 8, Article number: 44 (2018)

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                    • G Offline
                      G Offline
                      GeorgeBest
                      wrote on sidst redigeret af
                      #899

                      har tidligere læst her at markedet for amyloidosis har en størrelses på ca. 20% af MM markedet

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                      • J Offline
                        J Offline
                        JKY_VH
                        wrote on sidst redigeret af
                        #900

                        Mange tak Don. Så vidt jeg kan forstå er sygdommen arvelig.

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                        • J Offline
                          J Offline
                          JKY_VH
                          wrote on sidst redigeret af
                          #901

                          og tak GB:-)

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                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #902

                            noget kunne tyde på at dara virker endnu bedre i amyloisosis end i MM

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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #903

                              Kombinationen med CyBorD er også meget interessant i MM. Mener vi snart kan vente data.

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                              • B Offline
                                B Offline
                                bibob
                                wrote on sidst redigeret af
                                #904

                                Solsen. Resultater september. 18 . Men dog kun 18 patienter. If clinical trial. https://www.clinicaltrials.gov/ct2/show/NCT02955810?term=Dara%2BCyBorD&cond=MM&rank=1

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #905

                                  Der er også et fase 2 med 101 pts, der burde være data fra.

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                                  • SolsenS Offline
                                    SolsenS Offline
                                    Solsen
                                    wrote on sidst redigeret af
                                    #906

                                    https://www.clinicaltrials.gov/ct2/show/NCT02951819?term=Cybord&cond=Daratumumab&rank=3 8. marts 2018.

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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #907

                                      Ser ud til at rekruttering stoppede marts og primary endpoint måles ved 4 mdr. Så vi nærmer os.

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #908

                                        new country, Panama - Aprueban nuevo tratamiento para el Mieloma Múltiple en Panamá - https://www.tvn-2.com/nacionales/salud/Aprueban-tratamiento-Mieloma-Multiple-Panama_0_5079991985.html

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #909

                                          161 to go @bibob ? 😉

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