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Genmab — Maj 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • nohopeN Offline
    nohopeN Offline
    nohope
    wrote on sidst redigeret af
    #1790

    1025 ? Now you are talking 🙂

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    • G Offline
      G Offline
      gentogen
      wrote on sidst redigeret af
      #1791

      Som sagt bringer det hele denne gamle sag i erindring: Merck announced that it was postponing enrollment in KEYNOTE-183 and KEYNOTE-185 after an independent data monitoring committee noted an imbalance in deaths among patients with multiple myeloma assigned to combination therapy involving pembrolizumab and immunomodulatory treatment.

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      • P Offline
        P Offline
        pauly
        wrote on sidst redigeret af
        #1792

        omsætningen er da fin 🙂

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        • nohopeN Offline
          nohopeN Offline
          nohope
          wrote on sidst redigeret af
          #1793

          Yep, en skam man ikke får procenter. Men det er der andre der gør.

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #1794

            præcis gentogen - udfra denne har jeg i hvert fald konkluderet at PD-1 og PD-L1 ikke blev konkurrenter i MM

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            • G Offline
              G Offline
              gentogen
              wrote on sidst redigeret af
              #1795

              Selv om jeg er helt enig i, at Genmab ikke er ansvarlig for markedets reaktioner på pressemeddelelsen så er problemet vel alligevel lidt det, at et problem for PD1 opfattes som et problem for Dara (se blot Bowers mærkelige udlægning). . Det kunne man godt have undgået med en lidt anden ordlyd

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              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #1796

                Jeg synes Bowers skriveri virker modsatrettet - forstår det ikke helt

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                • Helge_LarsenPI-redaktørH Offline
                  Helge_LarsenPI-redaktørH Offline
                  Helge_LarsenPI-redaktør
                  wrote on sidst redigeret af
                  #1797

                  Jeg ved ikke rigtig i hvilket omfang Jan har hypet Dara i fste tumorer. Syntes mere at hans primære fokus har været andet steds:https://medwatch.dk/secure/Medicinal___Biotek/article10024820.ece

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                  • J Offline
                    J Offline
                    JohnW
                    wrote on sidst redigeret af
                    #1798

                    Testes Darzalex i kombi med andre stoffer (altså ikke PD-1) mod lungekræft?

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                    • S Offline
                      S Offline
                      Sukkeralf
                      wrote on sidst redigeret af
                      #1799

                      nej

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                      • J Offline
                        J Offline
                        JohnW
                        wrote on sidst redigeret af
                        #1800

                        Ok, tak.

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #1801

                          I don't think that Dara in solid is completely gone (yet...)...chances are smaller offcourse, but we can not exclude Mono or other new combinations
                          ?

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #1802

                            That is why i linked to Plesners video yesterday, where he said there was a reaction from Dara in NSCLC (even though a better one in the combo)

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #1803

                              I think it is to early to conclued

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #1804

                                conclude

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #1805

                                  A biotech company with nothing else to do might keep holding on to the dream - but a biotech company with other things to do would drop the idea at least for now. The preclinical rationale didnt work - move on ! Thats my view

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                                  • M Offline
                                    M Offline
                                    Mcjean
                                    wrote on sidst redigeret af
                                    #1806

                                    Not for me E L..........Fuck solid and concentrate or focus on primary goals;-)

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #1807

                                      Just keep focus on AXL - in my view it was worth more than dara i solid tumours before thing sad news

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                                      • Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktør
                                        wrote on sidst redigeret af
                                        #1808

                                        I think it is necessary to get an assessment of data and mechanisms associated with the study of small cell lung cancer before Janssen will judge Dara out
                                        in solid tumors.

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #1809

                                          yes, AXL i agree on

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