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Genmab — Juli 2017

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • G Offline
    G Offline
    gentogen
    wrote on sidst redigeret af
    #564

    Har denne været omtalt før?? “Conventional therapies used to treat MGRS don’t always work, which leaves the patient with few options,” said Sanjiv Anand, MD, MS, transplant nephrologist with the Intermountain Medical Center Kidney Transplantation Program, and lead author of the study. “After trying all the conventional therapies with our patient, we decided to go one step further and move forward with an off-label use of a relatively new drug called Daratumumab.”

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    • G Offline
      G Offline
      gentogen
      wrote on sidst redigeret af
      #565

      “Dr. Anand's work demonstrates the efficacy of Daratumumab in the setting of PGNMID,” added Titte Srinivas, MD, FAST, medical director of the Intermountain Medical Center Kidney Transplantation Program. “The ability of Daratumumab to directly target plasma cells affords a new way to treat plasma cell disorders with a positive impact on kidney function

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      • G Offline
        G Offline
        gentogen
        wrote on sidst redigeret af
        #566

        “Following seven doses of Daratumumab, the patient’s proteinuria numbers remarkably improved from 9.7 gm/d to only 0.7 gm/d and his renal function dramatically improved,” said Dr. Anand.

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        • G Offline
          G Offline
          gentogen
          wrote on sidst redigeret af
          #567

          Attention Required! | Cloudflare

          favicon

          (intermountainhealthcare.org)

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          • M Offline
            M Offline
            Mcjean
            wrote on sidst redigeret af
            #568

            Hvad er MGRS

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            • P Offline
              P Offline
              Plimsoller
              wrote on sidst redigeret af
              #569

              Hvad betyder "proteinuria numbers"?

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              • B Offline
                B Offline
                bibob
                wrote on sidst redigeret af
                #570

                @legolas og Nickstar. Ja vi vendelboer sætter ikke vores lys under en skæppe. 😄

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                • P Offline
                  P Offline
                  Plimsoller
                  wrote on sidst redigeret af
                  #571

                  Monoclonal gammopathy of renal significance (MGRS)

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                  • M Offline
                    M Offline
                    Mcjean
                    wrote on sidst redigeret af
                    #572

                    OK tak

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                    • M Offline
                      M Offline
                      Mcjean
                      wrote on sidst redigeret af
                      #573

                      Proteinuria = udskillelse af protien i urinen. Skal helst være ca. maks 0.5 gram pr dag.

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #574

                        lol, only real numbers count unfortunately Mcjean, so i am afraid JKY won the champagne with 300

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                        • P Offline
                          P Offline
                          Plimsoller
                          wrote on sidst redigeret af
                          #575

                          Tak:-)

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                          • M Offline
                            M Offline
                            Mcjean
                            wrote on sidst redigeret af
                            #576

                            He deserve it, he dont drink enough, but the numbers dont add up, something is wrong, and the correct number is 320.1

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                            • J Offline
                              J Offline
                              JKY_VH
                              wrote on sidst redigeret af
                              #577

                              😄

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                              • J Offline
                                J Offline
                                JKY_VH
                                wrote on sidst redigeret af
                                #578

                                Novods bud "The underlying Darzalex traction in the US has stagnated somewhat in Q2, which could be attributed to: 1) monthly and quarterly variations; 2) stocking variations; and 3) doctors awaiting the Pomalyst+Darzalex combo, which came in mid-June. Especially the latter could explain the flat performance in June versus May as we know that many doctors at ASCO expressed anticipation of the Pomalyst combo approval given that many patients need that specific combo as the majority have already

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                                • J Offline
                                  J Offline
                                  JKY_VH
                                  wrote on sidst redigeret af
                                  #579

                                  received a Revlimid containing regimen."

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                                  • F Offline
                                    F Offline
                                    flottenschmecker
                                    wrote on sidst redigeret af
                                    #580

                                    Tak jky. Det lyder rigtigt, hvad novod siger. Juli har kun 20 dage, men ketchupflasken bliver rystet godt og grundigt

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                                    • J Offline
                                      J Offline
                                      JKY_VH
                                      wrote on sidst redigeret af
                                      #581

                                      præcis, der er meget godt i vente.

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                                      • M Offline
                                        M Offline
                                        Mcjean
                                        wrote on sidst redigeret af
                                        #582

                                        Han glemmer vel pkt 4 at der er mange store forsøg søsat som kan give en kortvarig stagnering. Men forventer der opjusteres med en femmer når tallene rettes til, ligesom de cutter en femmer når $ falder. Desuden regner jeg med at Genmab sender halvdelen af de ikke "redegjorte" royalties direkte til Proinvestors festkasse, altså omkring en 7-8 mill. hvis vi regner med 12% royalties, det ville være fair nok.

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                                        • BudweisB Offline
                                          BudweisB Offline
                                          Budweis
                                          wrote on sidst redigeret af
                                          #583

                                          🙂 det bliver en fest!

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