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Genmab — Februar 2017

Planlagt Fastgjort Låst Flyttet Genmab
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  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #2920

    Mon ikke Winkel også tænker på deres samarbejde med BioNTech og Aduro - altså I/O bispecifikke antistoffer.

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    • SolsenS Offline
      SolsenS Offline
      Solsen
      wrote on sidst redigeret af
      #2921

      Tror godt vi kan glæde os til JNJs R&D day i maj 🙂

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      0
      • T Offline
        T Offline
        Thomas
        wrote on sidst redigeret af
        #2922

        Bulder, er det fordi safety er afdækket
        og optimal dose allerede er fastlagt at man starter fra fase 2?

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #2923

          vil jeg tro. F.eks. i atezo-kombien esperimenteres der ikke med dosis. Dara gives 16mg/kg og atezo 1200mg.

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          • T Offline
            T Offline
            Thomas
            wrote on sidst redigeret af
            #2924

            Årsagen til at køre fase 2 og ikke 3 er at fase 3 er langt mere omfattende/d
            yrere, så man vil gerne se lidt beviser i et mindre fase 2 først?

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #2925

              pas

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              • G Offline
                G Offline
                GlobalMacro
                wrote on sidst redigeret af
                #2926

                Recently I spoke with two experts in the field (biotech investors with biotech experience at board level) who believed Dara in combo I/O studies could be approved after phase 1/2 if the data is overwhelmingly positive and of course save. Just like Dara/PomM/Dex. I'm not an expert regarding the regulation so I’m not 100% sure this is true but if true than it could all move very fast and the stock price will probably already implement a big chunk of the future prognosed value when strong

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                • G Offline
                  G Offline
                  GlobalMacro
                  wrote on sidst redigeret af
                  #2927

                  when strong data comes out.

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #2928

                    Would be nice 🙂

                    1 Reply Last reply
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                    • Legolas23L Offline
                      Legolas23L Offline
                      Legolas23
                      wrote on sidst redigeret af
                      #2929

                      Castor og Pollux blev også standset, fordi man nåede endpoint før tid.

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                      0
                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #2930

                        men var dog fase 3

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                        0
                        • B Offline
                          B Offline
                          bibob
                          wrote on sidst redigeret af
                          #2931

                          Så snakker vi vel om 2 - 3 År og ikke 5-7 år.

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                          0
                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #2932

                            dara-atezo i nsclc har primærdata klar i juli 18!

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                            0
                            • B Offline
                              B Offline
                              bibob
                              wrote on sidst redigeret af
                              #2933

                              Altså noget hurtigere. Spændende.

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                              0
                              • SolsenS Offline
                                SolsenS Offline
                                Solsen
                                wrote on sidst redigeret af
                                #2934

                                Husk der godkendes kun i afprøvede indikationer - hvilket begrænser anvendelsen en del

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                                0
                                • G Offline
                                  G Offline
                                  GlobalMacro
                                  wrote on sidst redigeret af
                                  #2935

                                  Believe it only happens with significantly strong and safe data of drugs that are already tested in other indication and are found very safe. If then any significant Phase 1/2 data comes out it could mean it could get approved. Still, I don't have the regulation experience myself, this is just based on combining pure logic with facts that we know (sBLA Dara/Pom/Dex based on phase 1/2)

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                                  0
                                  • B Offline
                                    B Offline
                                    bibob
                                    wrote on sidst redigeret af
                                    #2936

                                    JP Morgan`s rating Genmab from neutral to overweight. http://petroglobalnews24.com/2017-02-28-genmab-as-gnmsf-raised-to-overweight-at-j-p-morgan-chase-co/

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                                    • J Offline
                                      J Offline
                                      JKY_VH
                                      wrote on sidst redigeret af
                                      #2937

                                      tak bibob, det luner alt sammen:-)

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                                      • B Offline
                                        B Offline
                                        bibob
                                        wrote on sidst redigeret af
                                        #2938

                                        Ja. Men jeg tror vi ser samme handelsmønster som i går. A/B er lidt på sælgersiden, men der er heldigvis købere.

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                                        • Legolas23L Offline
                                          Legolas23L Offline
                                          Legolas23
                                          wrote on sidst redigeret af
                                          #2939

                                          Fint købspres på baggrund af lille omsætning. Det lover godt..

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                                          0

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