Skip to content
  • Debatforum
  • Seneste
  • Populære
  • Bruger
Temaer
  • Light
  • Dark

Kollaps
FORSIDEN
Log ind Opret konto

Genmab — Februar 2017

Planlagt Fastgjort Låst Flyttet Genmab
3.0k Indlæg 1 Posters 0 Visninger
  • Ældste til nyeste
  • Nyeste til ældste
  • Most Votes
Svar
  • Svar som emne
Login for at svare
Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #2919

    De checkpoint studier med dara, der netop er startet er fase 2. Hvis de skal i fase 3, så taler vi vel om 5-7 år. Desuden kan vi vel regne med at både elo og isa melder sig som kandidater på det her felt.

    1 Reply Last reply
    0
    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #2920

      Mon ikke Winkel også tænker på deres samarbejde med BioNTech og Aduro - altså I/O bispecifikke antistoffer.

      1 Reply Last reply
      0
      • SolsenS Offline
        SolsenS Offline
        Solsen
        wrote on sidst redigeret af
        #2921

        Tror godt vi kan glæde os til JNJs R&D day i maj 🙂

        1 Reply Last reply
        0
        • T Offline
          T Offline
          Thomas
          wrote on sidst redigeret af
          #2922

          Bulder, er det fordi safety er afdækket
          og optimal dose allerede er fastlagt at man starter fra fase 2?

          1 Reply Last reply
          0
          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #2923

            vil jeg tro. F.eks. i atezo-kombien esperimenteres der ikke med dosis. Dara gives 16mg/kg og atezo 1200mg.

            1 Reply Last reply
            0
            • T Offline
              T Offline
              Thomas
              wrote on sidst redigeret af
              #2924

              Årsagen til at køre fase 2 og ikke 3 er at fase 3 er langt mere omfattende/d
              yrere, så man vil gerne se lidt beviser i et mindre fase 2 først?

              1 Reply Last reply
              0
              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #2925

                pas

                1 Reply Last reply
                0
                • G Offline
                  G Offline
                  GlobalMacro
                  wrote on sidst redigeret af
                  #2926

                  Recently I spoke with two experts in the field (biotech investors with biotech experience at board level) who believed Dara in combo I/O studies could be approved after phase 1/2 if the data is overwhelmingly positive and of course save. Just like Dara/PomM/Dex. I'm not an expert regarding the regulation so I’m not 100% sure this is true but if true than it could all move very fast and the stock price will probably already implement a big chunk of the future prognosed value when strong

                  1 Reply Last reply
                  0
                  • G Offline
                    G Offline
                    GlobalMacro
                    wrote on sidst redigeret af
                    #2927

                    when strong data comes out.

                    1 Reply Last reply
                    0
                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #2928

                      Would be nice 🙂

                      1 Reply Last reply
                      0
                      • Legolas23L Offline
                        Legolas23L Offline
                        Legolas23
                        wrote on sidst redigeret af
                        #2929

                        Castor og Pollux blev også standset, fordi man nåede endpoint før tid.

                        1 Reply Last reply
                        0
                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #2930

                          men var dog fase 3

                          1 Reply Last reply
                          0
                          • B Offline
                            B Offline
                            bibob
                            wrote on sidst redigeret af
                            #2931

                            Så snakker vi vel om 2 - 3 År og ikke 5-7 år.

                            1 Reply Last reply
                            0
                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #2932

                              dara-atezo i nsclc har primærdata klar i juli 18!

                              1 Reply Last reply
                              0
                              • B Offline
                                B Offline
                                bibob
                                wrote on sidst redigeret af
                                #2933

                                Altså noget hurtigere. Spændende.

                                1 Reply Last reply
                                0
                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #2934

                                  Husk der godkendes kun i afprøvede indikationer - hvilket begrænser anvendelsen en del

                                  1 Reply Last reply
                                  0
                                  • G Offline
                                    G Offline
                                    GlobalMacro
                                    wrote on sidst redigeret af
                                    #2935

                                    Believe it only happens with significantly strong and safe data of drugs that are already tested in other indication and are found very safe. If then any significant Phase 1/2 data comes out it could mean it could get approved. Still, I don't have the regulation experience myself, this is just based on combining pure logic with facts that we know (sBLA Dara/Pom/Dex based on phase 1/2)

                                    1 Reply Last reply
                                    0
                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #2936

                                      JP Morgan`s rating Genmab from neutral to overweight. http://petroglobalnews24.com/2017-02-28-genmab-as-gnmsf-raised-to-overweight-at-j-p-morgan-chase-co/

                                      1 Reply Last reply
                                      0
                                      • J Offline
                                        J Offline
                                        JKY_VH
                                        wrote on sidst redigeret af
                                        #2937

                                        tak bibob, det luner alt sammen:-)

                                        1 Reply Last reply
                                        0
                                        • B Offline
                                          B Offline
                                          bibob
                                          wrote on sidst redigeret af
                                          #2938

                                          Ja. Men jeg tror vi ser samme handelsmønster som i går. A/B er lidt på sælgersiden, men der er heldigvis købere.

                                          1 Reply Last reply
                                          0

                                          Hello! It looks like you're interested in this conversation, but you don't have an account yet.

                                          Getting fed up of having to scroll through the same posts each visit? When you register for an account, you'll always come back to exactly where you were before, and choose to be notified of new replies (either via email, or push notification). You'll also be able to save bookmarks and upvote posts to show your appreciation to other community members.

                                          With your input, this post could be even better 💗

                                          Tilmeld Log ind

                                          • Log ind

                                          • Har du ikke en konto? Tilmeld

                                          • Login or register to search.
                                          • First post
                                            Last post
                                          0
                                          • Debatforum
                                          • Seneste
                                          • Populære
                                          • Bruger