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Genmab — December 2016

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • B Offline
    B Offline
    bibob
    wrote on sidst redigeret af
    #1597

    Artikel på fierce biotech. - Loxo oncology. Loxo sets clock ticking on filing for first - in - class cancer drug. ( kan desværre ikke linke )

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    • J Offline
      J Offline
      JohnW
      wrote on sidst redigeret af
      #1598

      Loxo oppe med 35% idag.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1599

        About the pan-Canadian Oncology Drug Review (pCODR)
        Once Health Canada has approved a cancer drug for use in Canada, the
        country's provinces and territories must decide if the drug will be eligible for public reimbursement. The CADTH pan-Canadian Oncology Drug Review (pCODR) plays an important role in their decision-making processes.

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #1600

          https://www.cadth.ca/darzalex-multiple-myeloma-details

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #1601

            Final Recommendation/Notification to implement
            Issued for Daratumumab 16 Dec

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            • G Offline
              G Offline
              gentogen
              wrote on sidst redigeret af
              #1602

              Det er jo helt oforståeligt

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              • G Offline
                G Offline
                gentogen
                wrote on sidst redigeret af
                #1603

                Myeloma Canada submits that pERC failed to fully comprehend the gravity of this stage of disease in
                patients. At this stage, patients have run out of options for treatment and are close to death. In
                particular, the statement “there is a low probability that daratumumab would be cost-effective in this
                population compared to other treatments” is at best conjectural and at worst insensitive.

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                • G Offline
                  G Offline
                  gentogen
                  wrote on sidst redigeret af
                  #1604

                  What other
                  “cost-effective” treatments is pERC recommending for this patient population? At the very least, a
                  recommendation should have been made for a sub-section of the indicated population.

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                  • G Offline
                    G Offline
                    gentogen
                    wrote on sidst redigeret af
                    #1605

                    Myeloma Canada is of the opinion the pERC recommendations and comments are not supported by clinical
                    practices and are in fact contradictory to the evidence presented in the Clinical Guidance report.

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                    • G Offline
                      G Offline
                      gentogen
                      wrote on sidst redigeret af
                      #1606

                      pERC also made some
                      assumptions that are not supported by either our patient survey or by the clinician survey, with respect to
                      the administration of daratumumab.

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                      • G Offline
                        G Offline
                        gentogen
                        wrote on sidst redigeret af
                        #1607

                        Jeg kan desværre ikke kopiere fra selveafgørelsen men følg selv linket fra E L

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                        • digafarmD Offline
                          digafarmD Offline
                          digafarm
                          wrote on sidst redigeret af
                          #1608

                          https://www.cadth.ca/sites/default/files/pcodr/pcodr_daratumumab_darzalex_mm_fn_rec.pdf

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                          • digafarmD Offline
                            digafarmD Offline
                            digafarm
                            wrote on sidst redigeret af
                            #1609

                            En beslutning truffet 1/12 så vidt jeg kan se?

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                            • J Offline
                              J Offline
                              Jedi
                              wrote on sidst redigeret af
                              #1610

                              Undskyld, men jeg kan kun finde Final Recommendation fra 1/12, men hvor ser I afgørelsen? (Som skulle være faldet 16/12)

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                              • J Offline
                                J Offline
                                Jedi
                                wrote on sidst redigeret af
                                #1611

                                Eller der kommer måske bare ikke nogen notification ved negativ recommendation?

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                                • J Offline
                                  J Offline
                                  Jedi
                                  wrote on sidst redigeret af
                                  #1612

                                  En skandale for patienterne

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                                  • digafarmD Offline
                                    digafarmD Offline
                                    digafarm
                                    wrote on sidst redigeret af
                                    #1613

                                    Tror d. 16. er implementeringsdatoen p.b.a. deres recommendation fra d. 1.

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                                    • digafarmD Offline
                                      digafarmD Offline
                                      digafarm
                                      wrote on sidst redigeret af
                                      #1614

                                      Hvordan kan de komme frem til konklusionen om at darzalex ikke er kosteffektivt nok ift. andre behandlinger i min. 3. linje når det ikke har været et tema for FDA eller EM
                                      A?

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #1615

                                        Ja, det kan undre at de kan se så forskelligt på sagerne. Det hele er galt: for dyrt, for lidt effektivitet, for lang infusionstid, ingen bedre livskvalitet. Hvorfor har vi mon ikke hørt noget fra Janssen/Genmab? Kan de stadig være i dialog med de canadiske myndigheder?

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                                        • G Offline
                                          G Offline
                                          GeorgeBest
                                          wrote on sidst redigeret af
                                          #1616

                                          Genmab meddeler, at der er indsendt registreringsansøgning for daratumumab til behandling af recidiverende/refraktær myelomatose i Japan og opdaterer sine resultatforventninger

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