Genmab — Maj 2021
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God morgen.
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En subkutan version af amivantamab på vej https://meetinglibrary.asco.org/record/201164/abstract
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Sukker, ja det store Mariposa studie med 1000 pts har primary completion april 24. https://clinicaltrials.gov/ct2/show/NCT04487080?term=Amivantamab&draw=2&rank=4
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Gentogen, i ansøgningen fra 3. dec nævner de dog genmab. https://www.jnj.com/janssen-submits-application-to-u-s-fda-seeking-approval-of-amivantamab-for-the-treatment-of-patients-with-metastatic-non-small-cell-lung-cancer-with-egfr-exon-20-insertion-mutations
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Phase I study investigating the safety of stereotactic body radiotherapy (SBRT) with anti-PD-1 and anti-IL-8 for the treatment of multiple metastases in advanced solid tumors. https://meetinglibrary.asco.org/record/201166/abstract
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Early stage. Jeg har i dag oprettet en
Proinvestor Youtube kanal. Her vil der fremover komme masser af interviews og præsentationer med biotekfirmaer. Til produktionen har jeg hyret et stærkt team ind som tidligere har arbejdet i bla. DR som studievært, videoproduktion og redigering. Sign up her: https://www.youtube.com/watch?v=teTBHPJusm0 -
PS: Giv vores første reklamevideo et like. På forhånd tak og forsat god pinse.
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Fra E L lagt i Aktiesnakken ved en fejl kl. 9,50: "JNJ's version of Amivantamab development" https://twitter.com/JNJNews/status/1395828935330607104
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Se mit svar i tråden fra JNJ.
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Tak Stroka. Jan beholder vi i vores vante Q&A format.
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Ungee tak for link. Der går de heller ikke så meget i detaljer kan jeg se.
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Ifølge patentet er opfinderne J. Neissen, P. Parren og J. Schumann samt M. Chiu (tidligere JN) og Moores (JNJ) (patent us 95 93 164). Og som Genmab (og EL) henviser til, kan udviklingshistorien læses her https://www.jbc.org/action/showPdf?pii=S0021-9258(21)00427-0
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"Joost Neijssen, Luus Wiegman, and JanineSchuurman are employees of Genmab. Paul Parren was anemployee of Genmab when this work was completed. Rosa M.F.Cardoso, Kristen Chevalier, and Sheri Moores are employees ofJanssen Research & Development. Mark Chiu, Mark Anderson, andWilliam Strohl were employees of Janssen Research & Developmentwhen this work was completed".
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Udviklingen er sket på baggrund af Genmabs duobody-teknologi.
So I wasn't the only one to notice the absence of Genmab there...
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