Genmab — December 2020
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Hu hej...hvor det går.
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Er det ikke korrekt forstået at Roches glofitamab har mange flere grade 3 og 4 AE's end epco ? Det er da en stor fordel for epco ! https://haematologisktidsskrift.dk/sygdomme/lymfoma/786-bispecifikke-antistoffer-viser-stadig-imponerende-responsrater-mod-lymfekraeft.html
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De har flere, men vel ikke mange flere...
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Epco har ingen grade 3/4, mens Glofitamab havde 1 grade 3 of en grade 4
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AE hos Glofitamab var primært i de 2 første behandlinger
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Epco største fordel ligger p.t. ved subcu version, men rygter mener Roche også vil udvikle subcu til Glofitamab
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Hvis det lykkes, kan det potentielt reducere Glofitamab AEs
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US svigter igen i dag..:-D
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Men ind til videre mente Martin Hutchings at Epcoritamab førte racet...
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GB hvis du kigger her er det over 50% grade 3 eller 4 ? https://twitter.com/graham74GC/status/1335689743347179527/photo/3
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Men Novo shiner..:-)
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Peter, I fodnoterne til siden henvises der kun til 2 AEs grade 3 og 4
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CRS was reported in 63.5% but was only grade 3/4 in severity for 2 patients https://www.onclive.com/view/glofitamab-demonstrates-high-cr-rate-in-relapsed-refractory-nhl
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