Genmab — December 2020
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FierceBiotech -
ASH: J&J links subcut BCMA bispecific to 73% response rate, plots aggressive investment https://www.fiercebiotech.com/biotech/ash-j-j-links-subcut-bcma-bispecific-to-73-response-rate-plots-aggressive-investment -
"The responses, which J&J said deepened over time, were seen in patients failed by multiple other therapies. Across the study, patients had received a median of six prior lines of treatment. Almost 40% of the participants were refractory to two or more immunomodulatory agents, two or more proteasome inhibitors and an anti-CD38 therapy. Such patients have few treatment options today".
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5-6%
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Det tager tid før man kan konstatere om de vil æde af daras markedsandele
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Genmab har hexa-cd38 i baghånden, som måske er endnu bedre end T&T, også med 20% royalty
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Er hexacd38 en del af den nuværende partneraftale med JnJ, med samme royalty og en
forlængelse af patentet? -
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20% royalty til 2031, derefter 13-20%
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Tak GB. Er det normalt der ikke fremgår end date på perioden med 13-20 %?
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Med hexa-cd38 succes vil det fjerne en stor del af den potentielle downside på igangværende voldgift med JnJ?
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Ja
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Usmani havde forventet mere af dara/pom/dex https://twitter.com/szusmani/status/1335677535280128004?s=21
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