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Genmab — November 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • G Offline
    G Offline
    gdn55
    wrote on sidst redigeret af
    #572

    Måske derfor man skal beholde Genmab, eller købe inden de bliver købt

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    • E Offline
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      E_L
      wrote on sidst redigeret af
      #573

      yes, maybe. but i don't expect new data @AaBforever , more of a deep dive into what we know and more explanation

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      • E Offline
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        E_L
        wrote on sidst redigeret af
        #574

        regarding safety Bulder , is that based on the data
        we just saw?

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #575

          because before, i was worried about liver tox

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #576

            and it seems
            manageable

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #577

              Nordea think the liver side-effects may hinder going to high doses!

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              • E Offline
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                E_L
                wrote on sidst redigeret af
                #578

                that would make sense. maybe that is something we can hear about on friday. But from the data we saw today, i found it hard to find a strong correlation between dose and efficacy

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                • E Offline
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                  E_L
                  wrote on sidst redigeret af
                  #579

                  or dose and toxicity for that matter, we saw no data on that i think

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #580

                    It's based on the conclusion in the abstract

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #581

                      and you can be sure Genmab does know that data

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #582

                        yes, ok, me too

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #583

                          didn't winkel comment on the liver-issue recently? or was that dr5/dr5?

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #584

                            "29/3 09:33
                            af Sukkeralf
                            The problem with 4-1BB was liver tox if I remember what Jan said at some point - so with these new attempts where you only get them attivated in the microenviroment of the solid tumours it should avoid liver tox"

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                            • E Offline
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                              E_L
                              wrote on sidst redigeret af
                              #585

                              i think he also asked Jan in a QA about dr5 / liver tox, but Jan didnt really answer

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                              • E Offline
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                                E_L
                                wrote on sidst redigeret af
                                #586

                                Jan can be quite good at not answering if he doesnt want 😉

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                                • E Offline
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                                  E_L
                                  wrote on sidst redigeret af
                                  #587

                                  @GB 17:06 don't forget that he always knows more then we do

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                                  • E Offline
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                                    E_L
                                    wrote on sidst redigeret af
                                    #588

                                    (and that he has a lot more share then we do 😉 )

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #589

                                      (and sometimes then should be than 😉 )

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                                      • K Offline
                                        K Offline
                                        Klarussen
                                        wrote on sidst redigeret af
                                        #590

                                        @Mogan, jeg er knap 100% kontant, solgte ud før præsidentvalget i US. Har ikke haft Genmab nogle måneder og venter på godt entrypoint. Tror vi skal længere ned i hele markedet , 2150 er bare et fiktivt tal, men i det område køber jeg gerne igen. Tror meget stærkt på Genmab på den lange bane.

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                                        • K Offline
                                          K Offline
                                          Klarussen
                                          wrote on sidst redigeret af
                                          #591

                                          Har været inde og ude af Genmab en del gange, og tjent godt, men ville ønske jeg bare havde holdt fast fra starten og haft Helges kølige overblik 😉

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