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Genmab — Oktober 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktørH Offline
    Helge_LarsenPI-redaktør
    wrote on sidst redigeret af
    #661

    Q&A d. 27. nov. kl. 16.

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    • Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktørH Offline
      Helge_LarsenPI-redaktør
      wrote on sidst redigeret af
      #662

      Aktier/tendens: Vestas og DSV i fokus i nervøst marked: https://www.proinvestor.com/investornyt/669096/aktier-tendens-vestas-og-dsv-i-fokus-i-nervost-marked

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #663

        Daratumumab efficacy in extramedullary orbital myeloma https://onlinelibrary.wiley.com/doi/full/10.1002/ccr3.3458

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #664

          AMGEN: KYPROLIS® (carfilzomib) sales decreased 2% year-over-year driven by volume declines, as fewer new patients began treatment due to COVID-19. Early indications point to a strong launch of the new once-weekly KYPROLIS and DARZALEX® (daratumumab) combination regimen that was approved by the U.S. Food and Drug Administration (FDA) in August.

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #665

            Efficacy and safety of weekly carfilzomib (70 mg/m2), dexamethasone, and daratumumab (KdD70) is comparable to twice-weekly KdD56 while being a more convenient dosing option: a cross-study comparison of the CANDOR and EQUULEUS studies https://www.tandfonline.com/doi/full/10.1080/10428194.2020.1832672

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #666

              A global antiB cell strategy combining obinutuzumab and daratumumab in severe pediatric nephrotic syndrome https://link.springer.com/article/10.1007/s00467-020-04811-0

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #667

                we used to see ofatumumab articles for that...

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #668

                  Novartis is also starting a new trial for people with relapsing MS who switch to Kesimpta from another anti-CD20 monoclonal antibody therapy; ie. Ocrevus https://clinicaltrials.gov/ct2/show/NCT04486716

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #669

                    In addition, Novartis is exploring other avenues for Kesimpta’s clinical development, including plans to test the medication in children with MS. https://multiplesclerosisnewstoday.com/news-posts/2020/09/10/new-and-ongoing-trials-evaluating-kesimpta-including-as-switch-therapy/ “We are not stopping research into Kesimpta,” he added. “Research continues with Kesimpta to help more patients know of its value.”

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #670

                      Sarclisa sold 13mio in Q3, 18mio YTD

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #671

                        Sarclisa® was approved in March in the U.S. for the treatment of adults with relapsed refractory multiple myeloma (RRMM) who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and in June by the European Commission in certain adults with RRMM. Third-quarter Sarclisa® sales were €13 million of which €9 million was generated in the U.S. despite the challenging launch environment due to COVID-19. Sarclisa® is now launched in the U.S., Austria, Japan,

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #672

                          Switzerland, Canada and UK. Five additional commercial launches are expected by year-end.

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                          0
                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #673

                            The development of the combination of Sarclisa® and atezolizumab in squamous cell carcinoma of the head and neck has been terminated.

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #674

                              The multiple myeloma trial for SAR442257, an antiCD38 xCD28xCD3 trispecific antibody, dosed its first patient.

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                              • D Offline
                                D Offline
                                deleted-user
                                wrote on sidst redigeret af
                                #675

                                Thanks to @EL for pushing news feed today. The markets seems to appreciate the flow 🙂

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                                • D Offline
                                  D Offline
                                  deleted-user
                                  wrote on sidst redigeret af
                                  #676

                                  @E L

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                                  • D Offline
                                    D Offline
                                    deleted-user
                                    wrote on sidst redigeret af
                                    #677

                                    Sr
                                    y for the last 2 posts - originally regards to E L

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #678

                                      yeah, EL is the stock ticker for Estée Lauder lol (which trades over 200 so don't know where the 75.8 comes from). The funny thing is that each time somebody types it like that here, it trades down, always - . I hope that is not a reflection on me 😉

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                                      • H Offline
                                        H Offline
                                        Hamming
                                        wrote on sidst redigeret af
                                        #679

                                        Nyt fra Immatics https://investors.immatics.com/news-releases/news-release-details/immatics-presents-preclinical-proof-concept-data-tcr-bispecifics

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                                        • H Offline
                                          H Offline
                                          Hamming
                                          wrote on sidst redigeret af
                                          #680

                                          Spændende samarbejdspartner

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