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Genmab — Oktober 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • T Offline
    T Offline
    Teller
    wrote on sidst redigeret af
    #254

    mht. retssagen - Mon ikke Genmab selv skal have indgået en aftale om betaling af royaltyes, hvis der skal gælde sådan en... Ellers er det vel stadig afregning for det aktive komponent Genmab levere i en hvilken som helst drug... Jeg tror på ledelsen har styr på det, ellers bliver jeg MEGET skuffet med den hyre de får, alt inklusiv.

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    • D Offline
      D Offline
      Doublo
      wrote on sidst redigeret af
      #255

      God onsdag morgen. I modsætning til en sag der indankes for en domstol af en part, er begge parter i voldgiftsager enige om, af få afprøvet et tvivlsspørgsmål ved en uvildig instans. En klar fordel er, at parterne kan udpege en voldgiftdommer med specifik viden, på netop det område hvor tvivlen er opstået, hvor dommerne i en retssag ved domstolene er generalister. Hvis der ikke er en klokkeklar vinder i sagen, kan voldgiftdommeren også medvirke til forlig mellem parterne.

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      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #256

        God morgen. :_)

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        • T Offline
          T Offline
          transalp
          wrote on sidst redigeret af
          #257

          Go morgen.. 🙂

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          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #258

            Johnson & Johnson (JNJ) Management on Q3 2020 Results - Earnings Call Transcript https://seekingalpha.com/article/4378919-johnson-johnson-jnj-management-on-q3-2020-results-earnings-call-transcript?part=single

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #259

              The usual positive comments on Dara, but also on amivantamab

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #260

                "As we head into the fourth quarter, we look forward to additional planned submissions, most notably our U.S. filing of our BCMA CAR-T in multiple myeloma as well as the U.S. filing for amivantamab in non-small cell lung cancer.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #261

                  I would also point to some of the filings that we anticipate here in the near-term with respect to the CAR-T BCMA as well as amivantamab for non-small cell lung cancer, potentially on the horizon and part of the mix in 2021.

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #262

                    -Maybe I can take the question on the EGFR-cMet antibody amivantamab. It is a really exciting project for us. You asked about near-term and long-term. First on the antibody itself, it's a really interesting antibody. It's unique to us and it incorporates both EGFR binding peak and the CMS binding peak and CMS is common resistance mechanism for EGFR therapy. So it's both the primary mutation and the resistance mechanism at the same time.

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #263

                      The near-term plan is to go forward with an Exon 20 EGFR tumor, non-small cell lung cancer, there are really no good opportunities for patients with Exon 20 signatures. But that's how we will begin but our eyes are on the larger EGFR mutation market and patients in non-small lung cancer. So with time, we plan on exploring multiple lines of therapy and eventually all EGFR containing tumors."

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #264

                        JNJ pipeline https://www.investor.jnj.com/_document/jnj-pipeline-q3-2020?id=00000175-21bf-d7ee-a9fd-39bfc4380000

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #265

                          anything about filing for approval this year with amivantamab or anything about the new Duobody in the clinic?

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #266

                            I think 10:50 points to amivantamab filing in Q4?

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #267

                              Beyond that i can only find JNJ-7957 (BCMA/CD3), JNJ-7564 (GPRC5D/CD3) for planned filing 2020-2023

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #268

                                10:50 E L - ohh yes sorry !

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #269

                                  Thx E L

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #270

                                    I didn't realize we were that close to an amivantamab filing.

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #271

                                      Its going to be fun to see milestones for filing and approval to get a feeling about how backloaded these Duobody deals are

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                                      • bongobobB Offline
                                        bongobobB Offline
                                        bongobob
                                        wrote on sidst redigeret af
                                        #272

                                        Meget informativt om Amivantamab. 6-12 md approval...moving to 1.line... Beklager hvis den har været linket. https://www.docwirenews.com/hematology-oncology/amivantamab-plus-lazertinib-combo-show-promising-results-at-esmo-2020/

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                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #273

                                          SITC ID: 561
                                          DuoBody®-PD-L1×4-1BB (GEN1046) induces superior immune-cell activation, cytokine production and cytotoxicity by combining PD-L1 blockade with conditional 4-1BB co-stimulation https://sitc.planion.com/Web.User/AbstractDet?ACCOUNT=SITC&ABSID=13906&CONF=SITC20&ssoOverride=OFF&CKEY=

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