Genmab — August 2020
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“Approximately half of patients with light-chain amyloidosis have some degree of heart involvement and are sensitive to volume overload.Since daratumumab had to be given as a prolonged intravenous infusion with a significant amount of fluid volume, one of our main concerns had been aggravation of congestive heart failure in these patients.
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The subcutaneous administration is a significant advance that minimizes the chances of fluid overload and exacerbation of congestive heart failure. Additionally, the shorter infusion time may improve patients’ quality of life.” https://ascopost.com/issues/august-25-2020/epov-taimur-sher/
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Bryan Garnier yesterday:
GENMAB NEUTRAL | DKK2200 vs. DKK2150 Ofatumumab (now Kesimpta) approved in the US
1st subcutaneous anti-CD20 therapy to be approved for RMS
Three key characteristics resulting in a differentiated profile
Treatment practices are shifting towards high efficacy therapies
FV increased to DKK2200, Neutral rating confirmed -
Thanks E L .
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impressive how quickly JNJ adds new hospitals to the new Amivantamab trial. Should start in September https://www.clinicaltrials.gov/ct2/history/NCT04487080?A=1&B=2&C=merged#StudyPageTop
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Spørgsmål til Q&A er meget velkommen.
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Der har da godt nok været noget slagside på det sidste..:-(
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Det var bare en konstatering...:-)
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ja der burde være pæn støtte omkring 2280 - 2300. Men kanalen er brudt nedad så det bliver spændende hvad der sker resten af dagen og imo. Tror lige man skal klappe hesten men jeg har godt nok stop loss her på min spekulative portion. De lange holder jeg
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the CD3xCD33 JNJ duobody increased Enrollment: from 90 to 180 and it looks like they will try an SC version as well https://clinicaltrials.gov/ct2/history/NCT03915379?A=10&B=11&C=merged#StudyPageTop
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Spændende...og spændende..det ved jeg squ`ikke rigtig.
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Måske uhyggelig...spændende..;-)
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