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Genmab — August 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #166

    "Previously, trogocytosis was described as a mechanism of resistance for antibodies such as

    However, in this study, we demonstrated a novel role for

    trogocytosis (ADCT) as a crucial inducer of Fc-dependent receptor downmodulation and antitumor
    effects.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #167

      In addition to targeting a
      conserved region of an oncogenic receptor, which broadens the targeted population, the
      selectivity of bispecific antibodies like amivantamab, could offer a reduced potential for toxicity,
      making combination therapy with additional agents better tolerated.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #168

        Our findings demonstrate
        that the Fc-dependent activity of amivantamab is driven by macrophage- and monocyte-mediated
        trogocytosis, a dominant mechanism of antibody-directed receptor downregulation and tumor
        cell killing. These findings highlight the potential of trogocytosis as therapeutic modality but also
        provide insights to guide patient selection and combination strategies for amivantamab."

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #169

          BNT311 – BioNTech expects to provide a data update in 2H 2020, which will include dose-escalation data from the Phase 1/2 trial in multiple solid tumors for GEN1042/BNT311 (PD-L1x4-1BB). The program is partnered with Genmab. -as previously stated

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          • B Offline
            B Offline
            BioShare
            wrote on sidst redigeret af
            #170

            Om­sæt­nin­gen ven­tes at syv­dob­les - Børsen. https://borsen.dk/nyheder/virksomheder/i-genmab-regnskab-tikker-milliarder-fra-abbvie-aftale-ind-omsaetningen-ventes-at-syvdobles

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            • K Offline
              K Offline
              Klarussen
              wrote on sidst redigeret af
              #171

              SEB sænker anbefaling til SÆLG:
              https://www.euroinvestor.dk/nyheder/seb-om-genmab-saenker-anbefaling-til-saelg

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              • K Offline
                K Offline
                Klarussen
                wrote on sidst redigeret af
                #172

                Nu sv.t. kurs 2286 i US

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                • Legolas23L Offline
                  Legolas23L Offline
                  Legolas23
                  wrote on sidst redigeret af
                  #173

                  Du kan ikke bruge den amerikanske add til noget i forhold til næste dags danske åbningskurs. Casen og regnskabet i morgen bør have al opmærksomhed.

                  1 Reply Last reply
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                  • B Offline
                    B Offline
                    bikube
                    wrote on sidst redigeret af
                    #174

                    Horizon faldt 5,5%, det var da en røvfuld.

                    1 Reply Last reply
                    0
                    • Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktør
                      wrote on sidst redigeret af
                      #175

                      God morgen. 🙂

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                      • Helge_LarsenPI-redaktørH Offline
                        Helge_LarsenPI-redaktørH Offline
                        Helge_LarsenPI-redaktør
                        wrote on sidst redigeret af
                        #176

                        Husk at NBI index finder man i menulinjen under marked.

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                        • Helge_LarsenPI-redaktørH Offline
                          Helge_LarsenPI-redaktørH Offline
                          Helge_LarsenPI-redaktør
                          wrote on sidst redigeret af
                          #177

                          Her ligger også flere andre nyttige features.

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                          0
                          • B Offline
                            B Offline
                            bibob
                            wrote on sidst redigeret af
                            #178

                            God morgen. 🙂

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                            0
                            • T Offline
                              T Offline
                              transalp
                              wrote on sidst redigeret af
                              #179

                              Go morgen.. 🙂

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                              0
                              • M Offline
                                M Offline
                                Mogan
                                wrote on sidst redigeret af
                                #180

                                God Morgen 🙂

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                                0
                                • J Offline
                                  J Offline
                                  JKY_VH
                                  wrote on sidst redigeret af
                                  #181

                                  Novod løfter til 1872 fra 1811 og stadig hold.

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                                  0
                                  • J Offline
                                    J Offline
                                    JKY_VH
                                    wrote on sidst redigeret af
                                    #182

                                    ja sådan er det jo

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                                    0
                                    • S Offline
                                      S Offline
                                      Stroka
                                      wrote on sidst redigeret af
                                      #183

                                      SEB:

                                      • I øjeblikket virker det som om, at selskabet ikke kan noget forkert. Imidlertid mener vi, at aktien er mere end fuldt prissat, og vi sænker vores anbefaling til sælg, hedder det i notatet.

                                      Det nye kursmål indikerer et negativt potentiale i biotekaktien på 15 pct. i forhold til lukkekursen tirsdag i 2319 kr.

                                      SEB har i sine estimater indregnet et væsentligt højere bidrag fra øjenmidlet Tepezza, efter at selskabet bag markedsføringen Horizon har løftet sine forventninger til salget.

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                                      • Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktør
                                        wrote on sidst redigeret af
                                        #184

                                        SEB har hidtil haft en neutral anbefaling af aktien i Genmab siden januar 2019, da kursen på aktien lå i 1084 kr.

                                        /ritzau/FINANS

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                                        0
                                        • Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktørH Offline
                                          Helge_LarsenPI-redaktør
                                          wrote on sidst redigeret af
                                          #185

                                          Stroka..Husk kilde. 🙂

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                                          0

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