Genmab — Juni 2020
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Bispecifics er in og nu med CD28 https://finance.yahoo.com/news/publication-highlights-preclinical-research-showing-180000874.html
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I 2006 kørte et forsøg med CD28 fuldstændigt af sporet med patienter der røg på intensiv og vist nok flere døde. Man er heldigvis kommet videre siden.
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Har tjekket historien. Ingen døde, men oplevede voldsomme bivirkninger som var livstruende.
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Forsøget medførte at Torben Plesner og Genmab var ekstremt forsigtige med doseringen da man startede forsøg op med daratumumab.
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Community advice : SQ formulation of Daratumumab. ( transscript ) https://www.onclive.com/insights/daratumumab-subcutaneous-formulation-for-treatment-of-mm?eKey=amFuYm9ydXAxOTc4QGdtYWlsLmNvbQ==
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God morgen.
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Nikkei 225 i Tokyo faller 1,33 prosent
Kospi i Seoul faller 1,70 prosent
Singapore-børsen er ned 1,17 prosent
ASX 200 i Sydney faller 1,63 prosent -
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** Credit Suisse downgrades Danish pharmaceutical company Genmab GMAB.CO to "neutral" from "outperform" after it had found a material error in the PharmaValues net present value (NPV) calculation for the company
** Due to the error, the value of cancer drug Darzalex and chronic lymphocytic leukemia antibody ofatumumab royalties to Genmab were overstated, the brokerage says
** CS says its revised Genmab PharmaValues Equity NPV is DKK 1,800/share, reduced from DKK2,300/share seen previously -
** However, the error did not impact the broker's revenue or earnings model assumptions
** CS cuts it target price to DKK 2,235 from DKK 2,300 using the average Biotech and Specialty Pharma EV/NPV premium of 30%
** Following significant stock performance in H1 2020, the broker sees more limited near-term upside
** It still sees ofatumumab sales by partner Novartis NOVN.S as underappreciated
** It expects more modest further catalysts in H2 2020 following the positive AbbVie's ABBV.N oncology pa
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