Genmab — Maj 2020

[GeorgeBest]

[Helge_LarsenPI-redaktør]

[E_L]

Janssen press release - Janssen Presents First Data from Phase 1 Study of BCMAxCD3 Bispecific Teclistamab in Patients with Heavily Pretreated Relapsed or Refractory Multiple Myeloma https://www.prnewswire.com/news-releases/janssen-presents-first-data-from-phase-1-study-of-bcmaxcd3-bispecific-teclistamab-in-patients-with-heavily-pretreated-relapsed-or-refractory-multiple-myeloma-301060672.html

[E_L]

i wonder if there is a typo in this press release; where they say at a dose 'ranging from 0.3 µg/kg-720 µg/kg'
but then follow with 'At the 270 µg/kg dose' as they did in the abstract

[E_L]

Amivantamab presser: Janssen Announces Phase 1 Results for Bispecific Antibody Amivantamab in the Treatment of Patients with Advanced Non-Small Cell Lung Cancer Harboring Exon 20 Insertion Mutations https://www.janssen.com/janssen-announces-phase-1-results-bispecific-antibody-amivantamab-treatment-patients-advanced-non

[Sukkeralf]

dont think so - probably dose escalation up to 720 and dose expansion of the 270 ug dose (or maybe other doses)

[E_L]

could be , i thiught the 7 and the 2 might have been switched but it looks like a different cut off date is used for the presser

[E_L]

neutropenia now higher at 45% vs 26% abstract and anemia 58% vs 23% ; so a higher dose more toxic seems likely

[E_L]

and therefor expansion in the 270ug?

[E_L]

we will lik
ely hear more about it, as it is an oral presentation

[E_L]

Gen­mab tæt på kurs 2000, men kan den nå over 3000? Nemt, si­ger Citi https://borsen.dk/nyheder/virksomheder/genmab-taet-paa-kurs-2000-men-kan-den-naa-over-3000-nemt-siger-citi

[nohope]

Bent u Deens gaan spreken?

[E_L]

haha only when the headlines are this good

[E_L]

bluebird bio announced public offering of $400 million....

[Parasitism]

kom nu 3,5 kr!

[Parasitism]

haha - Jeg er næsten ligeglad med at den instantly falder tilbage igen - den skal bare lige runde!

[Mogan]

Nogen syntes, det er sjovt at lege kispus med os

[Parasitism]

Jeg synes vi skal rotte os sammen og købe den over

[Bulder]

Va' ska' vi dog med 2000, når vi ka' få 3?

[Mogan]

Jeg er fuldt lastet - men god idé.