Genmab — Maj 2020

[E_L]

"CD38-knockout NK cells, which have been designed in attempt to prevent fratricide and enhance the activity of daratumumab" https://twitter.com/MM_Hub/status/1260948019689795589

[Solsen]

At the moment its no competitor to dara. I think we now can say no thread to dara the next 5 years either from Takeda or JNJ.

[E_L]

you mean the JNJ car-t?

[Solsen]

yes

[Solsen]

I still think its for the last choise - due to sideeffects (possible grade 5) and price.

[E_L]

yea, think so too. Jan said that from the beginning, didn't he. The market clearly overshot in car-t optimism when it first came out, where in this chat most have been relatively negative

[Solsen]

With Car-T you manipulate with the immune system in a way that you dont have 100% control. Some pts just suddenly die.

[Solsen]

Perhaps not many but to many to first, second and perhaps third line.

[Solsen]

And thats where the big money are.

[Bulder]

Nevertheless it is very positive,that in the late lines, when all other options are used, there still is a possibility to have a sCR.

[Solsen]

You are so right !

[Solsen]

EPCORITAMAB has show its value today !

[Bulder]

It's almost like a cure. You can live for so many years with MM, that you'll die from age anyway.

[Solsen]

Until now nohope are right - we all die.

[nohope]

I may not be right about everything, but in this case I´m sure I´m right

[E_L]

[E_L]

some notable Asco presentations; includes epco https://www.evaluate.com/vantage/articles/events/conferences/asco-2020-abstract-dump-triggers-first-moves

[Solsen]

Just like waiting for christmas. Not many days before we se the partner.

[E_L]

second day of over 2 mio ADS in the US

[Darvin]

US vender også som “ventet” efter 2,5 dag