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Genmab — April 2020

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • K Offline
    K Offline
    kkjoel
    wrote on sidst redigeret af
    #385

    Ja men det må jo så betyder at de submitter for faseII, eller.. ?

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #386

      "The study seeks to determine the recommended Phase 2 dose in patients with advanced NSCLC.[5] Enrollment into the Part 2 dose expansion cohorts is ongoing" https://www.jnj.com/janssen-announces-u-s-fda-breakthrough-therapy-designation-granted-for-jnj-6372-for-the-treatment-of-non-small-cell-lung-cancer

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      • H Offline
        H Offline
        Hugininvest
        wrote on sidst redigeret af
        #387

        PS! Hos Genmab angives det at fase 2 er igang

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        • H Offline
          H Offline
          Hugininvest
          wrote on sidst redigeret af
          #388

          Men det samme siger JNJ jo, så CT er ikke opdateret

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #389

            Genmab siger det er i fase I/II. Part 2 er 2. del af fase 1

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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #390

              For mig lyder det som en lidt tidlig submission, da de end ikke har fundet RP2D.

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              • G Offline
                G Offline
                GeorgeBest
                wrote on sidst redigeret af
                #391

                submission i slutning af året...

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                • G Offline
                  G Offline
                  GeorgeBest
                  wrote on sidst redigeret af
                  #392

                  kan de nå at få nok evidens til slutning af året?

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                  • H Offline
                    H Offline
                    Hugininvest
                    wrote on sidst redigeret af
                    #393

                    Genmab: JNJ-61186372 is being investigated in Phase II clinical studies to treat non-small cell lung cancer (NSCLC). Lidt forvirrende, men konklusionen er at der er tro på det.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #394

                      åbenbart. Men et oplagt spm til Winkel for at få lidt klarhed.

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                      • G Offline
                        G Offline
                        GeorgeBest
                        wrote on sidst redigeret af
                        #395

                        enig, hvorfor skulle de ellers nævnte det på CC

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #396

                          Det står jo fint beskrevet i det link E L smed angående BTD - det er i EGFR Egon 20 mutationer, hvor der ikke er nogen godkendte terapier

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #397

                            Exon

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #398

                              ha ha

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                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #399

                                så det er unmet medical need

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #400

                                  Jeps

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                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #401

                                    der venter potentielt 10% royalties af en ny blockbuster. whats not to like 🙂

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #402

                                      mange bække små

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                                      0
                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #403

                                        it is also a potential SC candidate , according to Halozyme "In December, Janssen selected for development with ENHANZE® the targets EGFR and cMET on an exclusive basis as part of the bispecific antibody (JNJ-61186372), which is being studied in solid tumors."

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #404

                                          Thx E L

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                                          0

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