Genmab — Januar 2020
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God morgen.
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"Only one dose of daratumumab can decrease the amyloidogenic precursor immunoglobulin light chain protein rapidly and can lead to reversal of organ dysfunction in patients with AL amyloidosis" https://www.news-medical.net/news/20200127/Daratumumab-proves-effective-in-patients-with-relapsed-AL-amyloidosis.aspx
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God morgen
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God morgen.
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God morgen
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Dr. Shah on Daratumumab-Based Regimens in Frontline Multiple Myeloma https://www.youtube.com/watch?v=nbzuqc5vM5M
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Chinese Dara dose escalation study Completed
https://clinicaltrials.gov/ct2/history/NCT02852837?A=24&B=25&C=merged#StudyPageTop -
Mayo Dr. Sikander Ailawadh thinks maybe all MM patients needs two "shots" of CLR 131 before any other treatment. All MM patients receiving a split dosing af 37,5 ml CLR 131 in the ph2 Clover 1 trial had disease control and were progression free for 4 month and 50% with a ORR. Interesting to see if repeat dosing can extend durability. Video with Mayo Dr. from ASH commenting on CLR 131. https://www.youtube.com/watch?v=kHFmsr2_9cU&feature=youtu.be
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