Genmab — December 2019
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4 Questions for a Scientist Working on a Revolutionary CAR-T Therapy for Multiple Myeloma https://www.jnj.com/innovation/a-q-a-with-a-scientist-working-on-unique-car-t-therapy-for-multiple-myeloma
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MAIA study: second interim analysis results:https://multiplemyelomahub.com/medical-information/maia-study-second-interim-analysis-results
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Conclusion6
Patients with NDMM who are ineligible for ASCT had a 44% reduced risk of PD or death when treated with dara-Rd compared to Rd alone. Patients receiving dara-Rd had a longer PFS, higher response rate, increased the depth of response and longer duration of response compared to Rd.
Notably, in this trial, 99% of patients were aged 65 or older, and the PFS benefit was maintained regardless of age. The HR for PD or death in patients aged over 75 treated with dara-Rd was 0.63 reflecting
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Det er meget gode data, men ikke overraskende.
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bluebird bio to Present New Data from Gene and Cell Therapy Programs at 61st American Society of Hematology Annual Meetinghttps://www.bloomberg.com/press-releases/2019-11-06/bluebird-bio-to-present-new-data-from-gene-and-cell-therapy-programs-at-61st-american-society-of-hematology-annual-meeting-and
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Bluebird, Celgene Cancer Therapy Gets Boost From New Studyhttps://www.bloomberg.com/news/articles/2019-12-06/bluebird-celgene-cancer-therapy-gets-big-boost-from-new-study
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Keith Stewart
@akeithstewart
·Interesting thoughts from audience before and after debate on how to treat high risk myeloma this morning. https://twitter.com/akeithstewart/status/1202960281711861766 -
Pause herfra. Skal på arbejde i familiens butik. Marthine tager over lidt senere.
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New data show Bluebird, Bristol CAR-T drug could be pioneering myeloma therapy. Competitors may be close behind
https://www.statnews.com/2019/12/06/new-data-show-bluebird-bristol-car-t-drug-could-be-pioneering-myeloma-therapy-competitors-may-be-close-behind/ -
IMF har lagt deres video af det årlige pre-ASH symposium ud på nettet. Det er en nørdet sag på 2 3/4 time. Men prøv at spole frem til 2:25. Der kommer et meget relevant spm fra salen om hvad man gør i 2. linje, når en pt har fået dara i 1. linje og nu relapser. Fortsætter man med dara eller skifter man til noget helt andet. Meningerne er delte. Plesner er inde over med sit synspunkt. https://www.myeloma.org/IMF-ASH-Orlando
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