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Genmab — November 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #361

    Mim8 utilized the Duobody® platform / Novo Nordisk / hemophilia A https://ash.confex.com/ash/2019/webprogram/Paper122817.html

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    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #362

      Flot indtil videre. Gen3013 oral, og endvidere 6 orale dara præsentationer. Og chance for Andromeda som LB.

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      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #363

        7 orale

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #364

          Fandme flot !

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          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #365

            Så slipper konen for at tale med mig i aften 😉

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            • P Offline
              P Offline
              Peter_Panik
              wrote on sidst redigeret af
              #366

              @ The Note 10.30. Jeg har længe og er stadig yderst positiv på Genmab, og der kommer jo den ene gode historie efter den anden. Vi kan jo og har tidligere set, at andre "store" spillere har en trading interesse i aktien både på den korte og mellemlange bane, og det kan give udsving, som river de nervøse midt over.

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #367

                Vigtigt gen3013: All CRS events were non-severe and did not lead to discontinuation.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #368

                  i think that is the most important line I take away from it for now; safety was Jan's biggest concern, wasn't it. Seems ok so far.

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                  • G Offline
                    G Offline
                    gentogen
                    wrote on sidst redigeret af
                    #369

                    Lidt Ofa: HCVAD-O is a safe and highly effective regimen in pts with CD20+ Ph-negative B-ALL. This regimen achieves excellent outcomes in the AYA population (...) All but 1 pt (98%) achieved CR (2 after 2 cycles)...Using historical control pts, there was a trend towards improved OS with HCVAD-O versus HCVAD-R

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                    • SolsenS Offline
                      SolsenS Offline
                      Solsen
                      wrote on sidst redigeret af
                      #370

                      hexacd38 ser også spændende ud specielt i new diagnosed

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                      • G Offline
                        G Offline
                        gentogen
                        wrote on sidst redigeret af
                        #371

                        The preliminary analysis of the GELLC7 trial showed that the addition of consolidation with ofatumumab after 12 cycles of prior treatment with ibrutinib was well tolerated and elicited a deeper response.(...)In 20 patients receiving the consolidation with ofatumumab an improvement in response was observed, with 8/20 patients (40%) attaining a CR (7 patients converted PR to CR, and one patient SD to CR

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #372

                          Hex-cd38 er stærkere end dara til CDC. Og på niveau med dara til ADCC og ADCP.

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #373

                            and they are not afraid to say it. Hope they can get this into the clinic fast

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #374

                              862 Weekly Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab (wKRd-D) Combination Therapy Provides Unprecedented MRD Negativity Rates in Newly Diagnosed Multiple Myeloma: A Clinical and Correlative Phase 2 Study https://ash.confex.com/ash/2019/webprogram/Paper126378.html

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #375

                                695 Efficacy and Tolerability of (Ixa Dara dex) in Unfit and Frail Newly Diagnosed Multiple Myeloma (NDMM) Patients; Results of the Interim Efficacy Analysis of the Phase II HOVON 143 Study https://ash.confex.com/ash/2019/webprogram/Paper121694.html

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                                • BulderB Offline
                                  BulderB Offline
                                  Bulder
                                  wrote on sidst redigeret af
                                  #376

                                  862: Nice, 83% MRD-neg!

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #377

                                    from
                                    Luciano J Costa
                                    @End_myeloma
                                    https://ash.confex.com/ash/2019/webprogram/Paper123401.html
                                    This is big news. I honestly can't think of any other intervention in MM with this much impact in survival. Congratulations to the Alcyone team
                                    @mvmateos
                                    #ASH2019 #mmsm

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #378

                                      https://ir.genmab.com/news-releases/news-release-details/genmab-announces-financial-results-first-nine-months-2019

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #379

                                        Genmab is improving its 2019 financial guidance mainly due to positive foreign exchange movements between the USD and DKK resulting in increased milestone income and royalties on sales of DARZALEX

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                                        • M Offline
                                          M Offline
                                          Mcjean
                                          wrote on sidst redigeret af
                                          #380

                                          300mill?

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