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Genmab — November 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • B Offline
    B Offline
    bibob
    wrote on sidst redigeret af
    #238

    Ja, hvorfor kaste gode penge efter dårlige. Stå aldrig til søs. Lad de andre stå. 😉

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    • S Offline
      S Offline
      Sukkeralf
      wrote on sidst redigeret af
      #239

      Det betyder vel dybest set at Janssen ikke selv tror ret meget på det mere

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      • B Offline
        B Offline
        bibob
        wrote on sidst redigeret af
        #240

        Lærepenge er dyre. 😉

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #241

          Isa + atezo i kolorektal har måske data til næste år. Isa + atezo i Advanced Malignancies startede først sidste år, så der går en rum tid endnu inden data. Begge er fase 2. https://www.clinicaltrials.gov/ct2/results?cond=&term=isatuximab+atezolizumab&cntry=&state=&city=&dist=

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #242

            Problemet med denne passive tilgang er, at skulle Sanofi begynder at se positive resultater, så kan du være sikker på de holder kortene tæt til kroppen længst muligt, sålænge de fornemmer at Janssen ikke har gang i noget. Dermed ender man med at være relativt langt bagefter.

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #243

              Forstår dog godt at man vil have sc dosering i mål før man kaster sig over usikre studier i solide tumorer, hvor man i værste tilfald pludselig måske står med nogle dødsfald der kan kaste smuds over sc dara

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #244

                agree. and JNJ clearly stated that they would wait with solid until the SC approval, that part is not new.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #245

                  (why is Jan talking in the quiet period by the way??)

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #246

                    Probably just talking gibberish 🙂

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #247

                      thinking out-loud; given your concern on damaging the MM franchise with Dara solid trial; could they wait for HexaBody-CD38 and try it with that..?

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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #248

                        Yes and no for you could end up the same way that deaths in a solid trial could jepardize the LCM in MM

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #249

                          From the press announcement: "Next-generation HexaBody-CD38 could potentially add to the DARZALEX multiple myeloma franchise and expand the potential of CD38-targeted therapies in further indications" - could be solids

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                          • Helge_LarsenPI-redaktørH Offline
                            Helge_LarsenPI-redaktørH Offline
                            Helge_LarsenPI-redaktør
                            wrote on sidst redigeret af
                            #250

                            Kære venner. Jeg mangler i den grad spørgsmål til Q&A. Håber at de kommer hurtigst muligt. 🙂

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #251

                              You had a Q at 10:41 E L 😉

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #252

                                well ok then, i already asked when he expects to start the first trial, i'll also ask if he thinks it will make for a better option with solids

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #253

                                  Vi skulle da også gerne snart se en IND/CTA for DuoHexa-CD37

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                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #254

                                    maybe it is already in the report tomorrow, we have seen that before, they don't always do a separate press release

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                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #255

                                      Agree - but that would be nice

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #256

                                        Vi skal nok levere spørgsmål Helge 🙂

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                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #257

                                          Nogen forventninger til ASH abstracts i morgen:

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