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Genmab — Oktober 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1431

    And if you look at perhaps the most recent approval in cervical cancer, it was pembro and PD-1 high-expressers with a 14, that's 14% response rate, but they were durable responses. And if you look at chemotherapy that has been used in a lot of publications, there are, I would say the range is probably somewhere between 8% and maybe 16%, 17%

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #1432

      response rate sometimes with durations that are tiny measured in two months of duration whereas with a checkpoint you can get a year or so of duration, which is likely why it got approval, even with the de minimis response rate because it had duration.

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1433

        So, I think those maybe can help you give you some landmarks of what's out there and clearly we want to do well by patients and have the best response we can have with single agent, look at this in future in combination. Roger, do you have any color that you want to add beyond that?

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #1434

          Roger Dansey

          No, Clay I agree with your comment that the bar is set by historical precedent and we need to wait for the TV results to see how they match up.

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #1435

            Thanks GB and E L

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #1436

              From Q2 CC Jan said this:We also watching the landscape very, very carefully for next-generation technologies, which we think would complement our technology base, Emily. And of course, with the cash now on the bank, we actually -- we can actually move very swiftly and very quickly to actually broaden the technology base of the company, both product-wise and technology-wise. And you'll see examples of each one of those in the coming time, I believe

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              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #1437

                We have had the Tempus deal so what is next ?

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                • S Offline
                  S Offline
                  Sukkeralf
                  wrote on sidst redigeret af
                  #1438

                  1451 - mon der er noget på vej

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                  • M Offline
                    M Offline
                    Mcjean
                    wrote on sidst redigeret af
                    #1439

                    yep

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                    • M Offline
                      M Offline
                      Mcjean
                      wrote on sidst redigeret af
                      #1440

                      regnskab!

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #1441

                        Det eneste jeg rigtigt kan forestille mig kunne sive på forhånd er Andromeda-data.

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #1442

                          Der har jeg det nok liddt sådan, at jeg frygter Jan har været for optimistisk, at interim data først kommer næste år - men det var præcist noget sådan der kunne drive kursen

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                          • B Offline
                            B Offline
                            Bella1
                            wrote on sidst redigeret af
                            #1443

                            Tidligere på året var der en i tråden som "spåede" at Genmab ville ende i toppen af C25 ved årets udgang - noget tyder på at vedkommende får ret 🙂

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                            • Helge_LarsenPI-redaktørH Offline
                              Helge_LarsenPI-redaktørH Offline
                              Helge_LarsenPI-redaktør
                              wrote on sidst redigeret af
                              #1444

                              Spørgsmål til Q&A er meget velkommen allerede nu. 🙂

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                              • J Offline
                                J Offline
                                JKY_VH
                                wrote on sidst redigeret af
                                #1445

                                Du er vel for ubeskeden til at afsløre, hvem det var Bella1:-)

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                                • B Offline
                                  B Offline
                                  Bella1
                                  wrote on sidst redigeret af
                                  #1446

                                  Husker det ikke. Forleden sendte fruen mig ned efter min ugentlige Emmenthaler, - "det ka´du godt huske selv?", så jeg tøffede ned til købmanden og bad om min Altzheimer. Købmanden: "De mener Deres Emmenthaler?, nej-nej, svarede jeg, - Emmenthaler er jo det jeg fejler!" 🙂

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                                  • J Offline
                                    J Offline
                                    JKY_VH
                                    wrote on sidst redigeret af
                                    #1447

                                    😄

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                                    • R Offline
                                      R Offline
                                      runek
                                      wrote on sidst redigeret af
                                      #1448

                                      Så lige en nyhed fra Y-mabs. Er der nogen som har aktier i det selskab? Stifter af genmab har vist startet det. Tror de laver meget af det samme.

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                                      • E Offline
                                        E Offline
                                        E_L
                                        wrote on sidst redigeret af
                                        #1449

                                        Janssen Announces Health Canada Approval of DARZALEX® (daratumumab) in Combination with Lenalidomide and Dexamethasone for Newly Diagnosed Patients with Multiple Myeloma Who Are Transplant Ineligible https://www.newswire.ca/news-releases/janssen-announces-health-canada-approval-of-darzalex-r-daratumumab-in-combination-with-lenalidomide-and-dexamethasone-for-newly-diagnosed-patients-with-multiple-myeloma-who-are-transplant-ineligible-858079819.html

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                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #1450

                                          Nice .-)

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