Genmab — Oktober 2019
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GENMAB $GMAB: -4.8x - https://twitter.com/11Graphs/status/1189196451563352064
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Husk mine aftennyheder: https://www.proinvestor.com/chathistory/58/chat nyheder
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Breaking. Kæmpe ko vending. Briterne skal til valg. https://ekstrabladet.dk/nyheder/politik/kaempe-kovending-briterne-skal-til-valg/7853292
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God morgen.
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Fra SGEN Q3 rapport i går: Tisotumab Vedotin innovaTV 204 Pivotal Trial Data Expected in 2020: Seattle Genetics and Genmab previously reported the completion of enrollment in the innovaTV 204 pivotal trial of tisotumab vedotin in patients with recurrent and/or metastatic cervical cancer who have relapsed or progressed after standard of care treatment. Topline data from the trial are expected in the first half of 2020.
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thks GB and to add from the transcript: Q: So, you mentioned the upcoming trial results for the TV study in cervical cancer from the - TV-204 trial. Can you just remind us of sort of expectations for what are the clinical bars here in terms of efficacy for approvability?
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Clay Siegall
There is a lot there and maybe I'll give you a few comments, but Roger can also follow up. And if you look at relapsed cervical cancer, it's a grim prognosis, no one survives this. This is bad, and despite Carticel and vaccines. Not everyone gets vaccine across the globe and in the U.S. and so there is still unfortunately a need for therapies for relapsed cervical cancer.
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And if you look at perhaps the most recent approval in cervical cancer, it was pembro and PD-1 high-expressers with a 14, that's 14% response rate, but they were durable responses. And if you look at chemotherapy that has been used in a lot of publications, there are, I would say the range is probably somewhere between 8% and maybe 16%, 17%
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