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Genmab — August 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #1203

    your notes are better then mine 😉 I think there is still an ATRA-Dara trial open, but indeed, Jan at some point said there are better options

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #1204

      ATRA was a bit toxic, wasnt it

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      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #1205

        FP-162 says costs associated with
        rapid infusion vs normal infusion do not differ much. I am a bit surprised by that.

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #1206

          Total costs estimated
          for the standard rate was $137,200 and $122,200 for
          the rapid rate

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #1207

            Once again: Thanks for the tremendous job you are doing, E L, for the benefit of us all. 🙂

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            • B Offline
              B Offline
              Bella1
              wrote on sidst redigeret af
              #1208

              🙂

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #1209

                lol, almost done with this document

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #1210

                  did not know this combo yet? SP-142
                  Multi-agent therapy with pomalidomide,
                  bortezomib, doxorubicin, dexamethasone and
                  daratumumab (Pom-PAD-Dara) in relapsed/
                  refractory multiple myeloma

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                  • E Offline
                    E Offline
                    E_L
                    wrote on sidst redigeret af
                    #1211

                    SP-201
                    Changes in cardiac biomarkers with
                    daratumumab therapy in patients with light
                    chain amyloidosis

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #1212

                      Discussion: Our results show that dara treatment
                      rapidly lowered dFLC without worsening cardiac
                      biomarkers in AL...., dara does not
                      impart additional AL cardiac biomarker toxicity.
                      Thus, particularly among advanced cardiac patients,
                      dara should be considered as an early treatment.

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #1213

                        -it is very important to get the correct early treatment in amyloidosis to prevent organ damage

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #1214

                          SP-311 was a late breaking abstract
                          Phase II study of the combination of
                          daratumumab, ixazomib, pomalidomide, and
                          dexamethasone as salvage therapy in
                          relapsed/refractory multiple myeloma

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #1215

                            "well-tolerated and has shown early safety in an
                            initial safety run-in analysis. Enrollment continues in
                            an expansion cohort to assess efficacy."

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                            • B Offline
                              B Offline
                              Bullish
                              wrote on sidst redigeret af
                              #1216

                              Goddag. Fantastisk at produktet virker så godt, og også bliver lettere at anvende. Jeg har været i aktien i mange år, og den fylder godt i porteføljen. Jeg overvejer at rebalancere, og kikker på om det er nu. Når jeg ser en kursgraf med omsætning for den sidste uge, så er det påfaldende, at der bliver handlet en hel masse aktier lige før lukketid hver dag. Er der nogen der kan forklare det? Er det shortcovering eller er der en storinvestor? Hvem sælger mon?

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                              • SolsenS Offline
                                SolsenS Offline
                                Solsen
                                wrote on sidst redigeret af
                                #1217

                                Jeg synes det er under relativ lille omsætning at vi stiger. Så salgspres kan der vel ikke tales om.

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #1218

                                  Nærmere ser det ud til, at en højere kurs ikke kan lokke mange sælgere på banen er min vurdering.

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                                  • B Offline
                                    B Offline
                                    Bullish
                                    wrote on sidst redigeret af
                                    #1219

                                    Jeg taler ikke
                                    om kursudviklingen, men om det spike som handlet mængde har taget før lukketid hver dag.

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                                    • B Offline
                                      B Offline
                                      Bullish
                                      wrote on sidst redigeret af
                                      #1220

                                      Daytradere?

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #1221

                                        Jo men der er jo tilsvarende købere. Helt normalt i aktien at der handles en større mængde i lukkeauktionen.

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                                        • B Offline
                                          B Offline
                                          Bullish
                                          wrote on sidst redigeret af
                                          #1222

                                          Indexfonde og robotter (algoritmer) handler typisk ved lukketid kan jeg læse mig til 🙂

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